Zdhhc5 - zinc finger, DHHC domain containing 5 Gene

Also Known as Zisp; 1110032A17Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 228136

Summary

Enables palmitoyltransferase activity. Involved in positive regulation of pattern recognition receptor signaling pathway; positive regulation of protein localization to phagocytic vesicle; and positive regulation of protein localization to plasma membrane. Acts upstream of or within protein palmitoylation. Located in dendrite; phagocytic vesicle; and plasma membrane. Is expressed in early conceptus; eye; heart; oocyte; and trunk somite. Orthologous to human ZDHHC5 (zinc finger DHHC-type palmitoyltransferase 5). [provided by Alliance of Genome Resources, Apr 2022]

Zdhhc5 Products (1)

mRNA Protein Name
NM_144887.4 NP_659136.1 palmitoyltransferase ZDHHC5

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables palmitoyltransferase activity IDA
IDA: Inferred from direct assay
22325201 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
21820437 MGI
Biological Process GO Annotation Evidence References Source
involved in positive regulation of pattern recognition receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
31649195 MGI
involved in positive regulation of protein localization to phagocytic vesicle IMP
IMP: Inferred from mutant phenotype
31649195 MGI
involved in positive regulation of protein localization to plasma membrane IMP
IMP: Inferred from mutant phenotype
31649195 MGI
involved in positive regulation of pyroptotic inflammatory response IMP
IMP: Inferred from mutant phenotype
38530158 MGI
acts upstream of or within protein palmitoylation IDA
IDA: Inferred from direct assay
22325201 MGI
acts upstream of or within protein palmitoylation IMP
IMP: Inferred from mutant phenotype
21820437 MGI
Cellular Component GO Annotation Evidence References Source
located in dendrite IDA
IDA: Inferred from direct assay
22325201 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
22325201 MGI
is active in glutamatergic synapse IEP
IEP: Inferred from expression pattern
22325201 MGI
located in phagocytic vesicle IDA
IDA: Inferred from direct assay
31649195 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
21820437 MGI
is active in postsynapse IDA
IDA: Inferred from direct assay
22325201 MGI
is active in postsynapse IEP
IEP: Inferred from expression pattern
22325201 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

palmitoyltransferase ZDHHC5

  • DHHC-5

  • probable palmitoyltransferase ZDHHC5

  • zinc finger DHHC domain-containing protein 5

Zdhhc5 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Zdhhc5 Q8VDZ4 GOLGA7B Mus musculus Q9D428
Anti Bait CoIP
31402609
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16022 ZDHHC5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21221 Zdhhc5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27737 Zdhhc5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Zdhhc5 NCBI NCBI:25921