2. Gene
  3. ZDHHC5 - zinc finger DHHC-type palmitoyltransferase 5 Gene

ZDHHC5 - zinc finger DHHC-type palmitoyltransferase 5 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as DHHC5; ZNF375

Gene ID: 25921 | Gene type: protein coding

About ZDHHC5

Cytogenetic location: 11q12.1 Genomic coordinates (GRCh38): 11:57,668,114-57,701,182 (from NCBI)

This gene has 8 transcripts (splice variants), 274 orthologues and 1 paralogue. Ubiquitous expression in esophagus (RPKM 30.1), thyroid (RPKM 23.7) and 25 other tissues.

Summary

Enables palmitoyltransferase activity. Involved in positive regulation of pattern recognition receptor signaling pathway and positive regulation of protein localization to plasma membrane. Acts upstream of or within protein palmitoylation. Located in phagocytic vesicle and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

ZDHHC5 Products(1)

mRNA Protein Name
NM_015457.3 NP_056272.2 palmitoyltransferase ZDHHC5

ZDHHC5 Protein Structure

DHHC

DHHC: DHHC palmitoyltransferase (62 - 222)

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  • 200
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  • 715 a.a.
Protein Preferred Names Protein Names

palmitoyltransferase ZDHHC5

DHHC-5

Related Diseases

Diseases Alias
Lung Acinar Adenocarcinoma

Acinar Adenocarcinoma Of The Lung
Lung Papillary Adenocarcinoma

Papillary Lung Adenocarcinoma

Papillary Adenocarcinoma Of The Lung
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS16022 ZDHHC5 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus ZDHHC5 MGD MGI:1923573
Bos taurus ZDHHC5 VGNC VGNC:37143
Macaca mulatta ZDHHC5 VGNC VGNC:79145
Felis catus ZDHHC5 VGNC VGNC:67216
Rattus norvegicus ZDHHC5 RGD RGD:1589737