SV2C - synaptic vesicle glycoprotein 2C Gene

Homo sapiens

Also known as SLC22B3

Gene ID: 22987 | Gene type: protein coding

About SV2C

Cytogenetic location: 5q13.3 Genomic coordinates (GRCh38): 5:75,847,464-76,353,939 (from NCBI)

This gene has 3 transcripts (splice variants), 276 orthologues and 2 paralogues. Biased expression in brain (RPKM 1.2), adrenal (RPKM 0.7) and 8 other tissues.

Summary

Predicted to enable transmembrane transporter activity. Predicted to be involved in chemical synaptic transmission; neurotransmitter transport; and transmembrane transport. Predicted to be located in plasma membrane and synaptic vesicle. Predicted to be active in neuron projection and synaptic vesicle membrane. Predicted to be integral component of synaptic vesicle membrane. [provided by Alliance of Genome Resources, Apr 2022]

SV2C Products(2)

mRNA	Protein	Name
NM_001297716.2	NP_001284645.1	synaptic vesicle glycoprotein 2C isoform 2
NM_014979.4	NP_055794.3	synaptic vesicle glycoprotein 2C isoform 1

SV2C Protein Structure

Sugar_tr

Pentapeptide_4

MFS_1

0
200
400
600
727 a.a.

Protein Preferred Names

Protein Names

synaptic vesicle glycoprotein 2C

solute carrier family 22 member B3

Related Diseases

Diseases

Alias

Foodborne Botulism

Botulism	Botulism Poisoning
Intoxication With Clostridium Botulinum Toxin	Wound Botulism
Food Poisoning Due To Clostridium Botulinum	Infection Due To Clostridium Botulinum
Infant Botulism	Intoxication Botulism
Botulism, Infantile	Clostridium Botulinum Poisoning
Botulism Nos

Intestinal Botulism

Intestinal Colonization Botulism	Intestinal Toxemia Botulism
Intestinal Toxin-Mediated Botulism

Infant Botulism

Infant Intestinal Botulism	Infant Intestinal Toxemia Botulism
Infant Intestinal Toxin-Mediated Botulism	Infantile Botulism
Botulism, Infantile

Wound Botulism

Cutaneous Infectious Botulism	Cutaneous Toxin-Mediated Botulism
Inoculation Botulism	Skin Infectious Botulism
Skin Toxin-Mediated Botulism

Benign Epilepsy With Centrotemporal Spikes

Rolandic Epilepsy	Benign Rolandic Epilepsy
Epilepsy, Rolandic	Bcects
Benign Childhood Epilepsy With Centrotemporal Spike	Sylvan Seizures
Becrs	Bects
Bre	Benign Epilepsy Of Childhood With Centrotemporal Spikes
Benign Familial Epilepsy Of Childhood With Rolandic Spikes	Centrotemporal Epilepsy

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14056	SV2C Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Bos taurus	SV2C	VGNC	VGNC:35496
Macaca mulatta	SV2C	VGNC	VGNC:78252
Felis catus	SV2C	VGNC	VGNC:65862
Mus musculus	SV2C	MGD	MGI:1922459
Rattus norvegicus	SV2C	RGD	RGD:619718
Canis familiaris	SV2C	VGNC	VGNC:47005