Adgrb2 - adhesion G protein-coupled receptor B2 Gene

Also Known as Bai2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 230775

Summary

Predicted to enable G protein-coupled receptor activity. Acts upstream of or within peripheral nervous system development and positive regulation of synapse assembly. Predicted to be located in plasma membrane. Predicted to be integral component of plasma membrane. Is expressed in several structures, including central nervous system; endocrine gland; genitourinary system; spleen; and visual system. Orthologous to human ADGRB2 (adhesion G protein-coupled receptor B2). [provided by Alliance of Genome Resources, Apr 2022]

Adgrb2 Products (7)

mRNA Protein Name
NM_001199696.2 NP_001186625.1 adhesion G protein-coupled receptor B2 isoform 2 precursor
NM_001290714.2 NP_001277643.1 adhesion G protein-coupled receptor B2 isoform 4 precursor
NM_001290715.2 NP_001277644.1 adhesion G protein-coupled receptor B2 isoform 3 precursor
NM_001377056.1 NP_001363985.1 adhesion G protein-coupled receptor B2 isoform 5 precursor
NM_001377057.1 NP_001363986.1 adhesion G protein-coupled receptor B2 isoform 6 precursor
NM_001377058.1 NP_001363987.1 adhesion G protein-coupled receptor B2 isoform 7 precursor
NM_173071.4 NP_775094.2 adhesion G protein-coupled receptor B2 isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
16412436 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within peripheral nervous system development IDA
IDA: Inferred from direct assay
12218411 MGI
acts upstream of or within positive regulation of synapse assembly IDA
IDA: Inferred from direct assay
24613359 MGI
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
31171447 MGI
is active in synapse IDA
IDA: Inferred from direct assay
31171447 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

adhesion G protein-coupled receptor B2

  • G protein-coupled receptor brain-specific angiogenesis inhibitor 1

  • brain-specific angiogenesis inhibitor 2

Adgrb2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Cross
Adgrb2 Q8CGM1 GABPB1 Homo sapiens Q06547
Y2H
16412436
Cross
Adgrb2 Q8CGM1 GABPB1 Homo sapiens Q06547
Pull Down
16412436
Cross
Adgrb2 Q8CGM1 GABPB1 Homo sapiens Q06547
Y2H Array
16412436
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00346 ADGRB2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19763 Adgrb2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26260 Adgrb2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Adgrb2 NCBI NCBI:576