Creb5 - cAMP responsive element binding protein 5 Gene

Also Known as Crebpa; CRE-BPa; 9430076C15Rik; D430026C09Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 231991

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific. Involved in white fat cell differentiation. Acts upstream of or within adipose tissue development; fat cell differentiation; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including forelimb bud; hindlimb phalanx; limb mesenchyme; oral epithelium; and telencephalon ventricular layer. Orthologous to human CREB5 (cAMP responsive element binding protein 5). [provided by Alliance of Genome Resources, Apr 2022]

Creb5 Products (2)

mRNA Protein Name
NM_001327821.1 NP_001314750.1 cyclic AMP-responsive element-binding protein 5 isoform 1
NM_172728.2 NP_766316.1 cyclic AMP-responsive element-binding protein 5 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: Inferred from direct assay
19948881 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within adipose tissue development IGI
IGI: Inferred from genetic interaction
19948881 MGI
acts upstream of or within fat cell differentiation IGI
IGI: Inferred from genetic interaction
19948881 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
19948881 MGI
involved in white fat cell differentiation IGI
IGI: Inferred from genetic interaction
19948881 MGI
involved in white fat cell differentiation IMP
IMP: Inferred from mutant phenotype
19948881 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
19948881 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cyclic AMP-responsive element-binding protein 5

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03154 CREB5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21540 Creb5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28058 Creb5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Creb5 NCBI NCBI:9586