Oscar - osteoclast associated receptor Gene

Also Known as mOSCAR; mOSCAR-M1; mOSCAR-M2; mOSCAR-M3

Species: Mus musculus

Gene Type: protein coding
Gene ID: 232790

Summary

Enables Collagen receptor activity. Acts upstream of or within Fc-gamma Receptor signaling pathway; multinuclear osteoclast differentiation; and positive regulation of bone resorption. Located in cell surface. Is expressed in testis. Orthologous to human OSCAR (osteoclast associated Ig-like receptor). [provided by Alliance of Genome Resources, Apr 2022]

Oscar Products (2)

mRNA Protein Name
NM_001290377.1 NP_001277306.1 osteoclast-associated immunoglobulin-like receptor isoform 2 precursor
NM_175632.3 NP_783440.1 osteoclast-associated immunoglobulin-like receptor isoform 1 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables collagen receptor activity IMP
IMP: Inferred from mutant phenotype
21841309 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
15184345 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within Fc-gamma receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
21841309 MGI
acts upstream of or within interleukin-2 production IGI
IGI: Inferred from genetic interaction
15184345 MGI
acts upstream of or within interleukin-2 production IPI
IPI: Inferred from physical interaction
15184345 MGI
acts upstream of or within multinuclear osteoclast differentiation IMP
IMP: Inferred from mutant phenotype
11805147 MGI
acts upstream of or within osteoclast differentiation IDA
IDA: Inferred from direct assay
21841309 MGI
acts upstream of or within osteoclast differentiation IGI
IGI: Inferred from genetic interaction
21841309 MGI
acts upstream of or within osteoclast differentiation IMP
IMP: Inferred from mutant phenotype
21841309 MGI
acts upstream of or within positive regulation of bone resorption IMP
IMP: Inferred from mutant phenotype
11805147 MGI
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
11805147 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

osteoclast-associated immunoglobulin-like receptor

  • ocl178

  • osteoclast-associated receptor OSCAR

Recombinant Oscar Proteins

Cat. No. Product Name Accession Purity
HY-P78012 OSCAR Protein, Mouse (HEK293, Fc) Q8VBT3-1 (D19-N228) ≥ 95%, as determined by Bis-Tris PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09847 OSCAR Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19466 Oscar Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25959 Oscar Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P992285 Anti-OSCAR Antibody / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Oscar NCBI NCBI:126014