1. Recombinant Proteins
  2. Receptor Proteins
  3. OSCAR Protein, Mouse (HEK293, Fc)

OSCAR Protein is a crucial regulator of osteoclastogenesis, playing a significant role in osteoclast differentiation within the bone. OSCAR Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived OSCAR protein, expressed by HEK293 , with C-hFc labeled tag.

For research use only. We do not sell to patients.

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Description

OSCAR Protein is a crucial regulator of osteoclastogenesis, playing a significant role in osteoclast differentiation within the bone. OSCAR Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived OSCAR protein, expressed by HEK293 , with C-hFc labeled tag.

Background

OSCAR Protein is a crucial regulator of osteoclastogenesis and plays a significant role in osteoclast differentiation, specifically within the bone.

Species

Mouse

Source

HEK293

Tag

C-hFc

Accession

Q8VBT3-1 (D19-N228)

Gene ID
Molecular Construction
N-term
OSCAR (D19-N228)
Accession # Q8VBT3-1
hFc
C-term
Protein Length

Extracellular Domain

Synonyms
mOSCAR; OSCAR; PIGR3; PIgR-3; Poly-Ig receptor 3; MGC33613
AA Sequence

DFTPTAPLASYPQPWLGAHPAAVVTPGINVTLTCRAPQSAWRFALFKSGLVTPLLLRDVSVELAEFFLEEVTPAQGGSYHCRYRKTDWGPGVWSQPSNVLELLVTDQLPRPSLVALPGPVVAPGANVSLRCAGRIPGMSFALYRVGVATPLQYIDSVQPWADFLLIGTHTPGTYCCYYHTPSAPYVLSQRSQPLVISFEGSGSLDYTQGN

Predicted Molecular Mass
49.7 kDa
Molecular Weight

Approximately 60-70 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.

Glycosylation
Yes
Purity

≥ 95%, as determined by Bis-Tris PAGE.

Appearance

Lyophilized powder

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 8% trehalose is added as protectant before lyophilization.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.

Storage & Stability

Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Documentation

OSCAR Protein, Mouse (HEK293, Fc) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
OSCAR Protein, Mouse (HEK293, Fc)
Cat. No.:
HY-P78012
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