Siglecf - sialic acid binding Ig-like lectin F Gene
Also Known as Siglec5; mSiglec-F
Species: Mus musculus
Summary
Enables monosaccharide binding activity and sialic acid binding activity. Involved in regulation of endocytosis. Located in lysosome. Orthologous to several human genes including SIGLEC6 (sialic acid binding Ig like lectin 6). [provided by Alliance of Genome Resources, Apr 2022]
Siglecf Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001271019.1 | NP_001257948.1 | sialic acid-binding Ig-like lectin 5 isoform 2 precursor |
| NM_145581.2 | NP_663556.1 | sialic acid-binding Ig-like lectin 5 isoform 1 precursor |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables monosaccharide binding |
IDA
IDA: Inferred from direct assay
|
15048729 | MGI |
| enables sialic acid binding |
IDA
IDA: Inferred from direct assay
|
17562860 | MGI |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| involved in regulation of endocytosis |
IDA
IDA: Inferred from direct assay
|
17562860 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| located in lysosome |
IDA
IDA: Inferred from direct assay
|
17562860 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
sialic acid-binding Ig-like lectin 5 |
|
|
Recombinant Siglecf Proteins
| Cat. No. | Product Name | Accession | Purity |
|---|---|---|---|
| HY-P72470 | Siglec-F Protein, Mouse (HEK293, His) | Q920G3 (D18-T437) | ≥ 95%, as determined by reducing SDS-PAGE. |
| HY-P78354 | Siglec-5 Protein, Mouse (HEK293, His) | Q920G3 (T17-L439) | ≥ 95%, as determined by Bis-Tris PAGE. |