TMED3 - transmembrane p24 trafficking protein 3 Gene

Also Known as p26; P24B; p24g4; C15orf22; p24gamma4

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 23423

About TMED3

This gene has 5 transcripts (splice variants), 179 orthologues and 8 paralogues. Ubiquitous expression in salivary gland (RPKM 12.9), thyroid (RPKM 6.0) and 23 other tissues.

Summary

Predicted to be involved in Golgi organization; endoplasmic reticulum to Golgi vesicle-mediated transport; and intracellular protein transport. Located in Golgi apparatus; endoplasmic reticulum; and endoplasmic reticulum-Golgi intermediate compartment. [provided by Alliance of Genome Resources, Apr 2022]

TMED3 Products (4)

mRNA Protein Name
NM_001301203.3 NP_001288132.1 transmembrane emp24 domain-containing protein 3 isoform b precursor
NM_001330376.2 NP_001317305.1 transmembrane emp24 domain-containing protein 3 isoform c precursor
NM_001363735.2 NP_001350664.1 transmembrane emp24 domain-containing protein 3 isoform d precursor
NM_007364.4 NP_031390.1 transmembrane emp24 domain-containing protein 3 isoform a precursor

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in Golgi apparatus IDA
IDA: Inferred from direct assay
12237308 GOA
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
12237308 GOA
located in endoplasmic reticulum-Golgi intermediate compartment IDA
IDA: Inferred from direct assay
12237308 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TMED3 Protein Structure

EMP24_GP25L

EMP24_GP25L: emp24/gp25L/p24 family/GOLD (29 - 205)

  • 0
  • 100
  • 200
  • 217 a.a.
Protein Preferred Names Protein Names

transmembrane emp24 domain-containing protein 3

  • integral type I protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14637 TMED3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21789 Tmed3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28305 Tmed3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris TMED3 VGNC VGNC:47438
Bos taurus TMED3 VGNC VGNC:35936
Mus musculus TMED3 MGD MGI:1913361
Macaca mulatta TMED3 VGNC VGNC:79750
Rattus norvegicus TMED3 RGD RGD:1303327
Felis catus TMED3 VGNC VGNC:66248
Others TMED3 NCBI