Klf6 - Kruppel-like factor 6 Gene

Also Known as FM2; FM6; Zf9; BCD1; CPBP; Copeb; Ierepo1; Ierepo3

Species: Mus musculus

Gene Type: protein coding
Gene ID: 23849

Summary

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of connective tissue replacement. Acts upstream of or within cytokine-mediated signaling pathway. Located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; early conceptus; embryo mesenchyme; genitourinary system; and peripheral nervous system. Human ortholog(s) of this gene implicated in prostate Cancer. Orthologous to human KLF6 (Kruppel like factor 6). [provided by Alliance of Genome Resources, Apr 2022]

Klf6 Products (1)

mRNA Protein Name
NM_011803.2 NP_035933.2 Krueppel-like factor 6

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within cytokine-mediated signaling pathway IDA
IDA: Inferred from direct assay
10880228 MGI
involved in positive regulation of connective tissue replacement IMP
IMP: Inferred from mutant phenotype
22820290 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
15557439 MGI
located in nucleus IDA
IDA: Inferred from direct assay
15557439 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

Krueppel-like factor 6

  • core promoter element binding protein

  • immediate early response, erythropoietin 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07343 KLF6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17094 Klf6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23538 Klf6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Klf6 NCBI NCBI:1316