Osr1 - odd-skipped related transcription factor 1 Gene

Also Known as Osr; Odd1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 23967

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including animal organ development; embryonic limb morphogenesis; and regulation of transcription by RNA polymerase II. Acts upstream of or within animal organ development; cellular response to retinoic acid; and intermediate mesoderm development. Predicted to be located in cytosol. Predicted to be extrinsic component of membrane. Predicted to be active in nucleus. Is expressed in several structures, including branchial arch; central nervous system; embryo mesenchyme; genitourinary system; and limb. Orthologous to human OSR1 (odd-skipped related transcription factor 1). [provided by Alliance of Genome Resources, Apr 2022]

Osr1 Products (1)

mRNA Protein Name
NM_011859.3 NP_035989.1 protein odd-skipped-related 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
24598167 MGI
Biological Process GO Annotation Evidence References Source
involved in cell differentiation IGI
IGI: Inferred from genetic interaction
21262216 MGI
involved in cell proliferation involved in kidney development IMP
IMP: Inferred from mutant phenotype
16790474 MGI
involved in cellular response to retinoic acid IEP
IEP: Inferred from expression pattern
20171952 MGI
involved in chondrocyte differentiation IGI
IGI: Inferred from genetic interaction
21262216 MGI
involved in embryonic digit morphogenesis IGI
IGI: Inferred from genetic interaction
21262216 MGI
involved in embryonic forelimb morphogenesis IGI
IGI: Inferred from genetic interaction
21262216 MGI
involved in embryonic hindlimb morphogenesis IGI
IGI: Inferred from genetic interaction
21262216 MGI
involved in embryonic skeletal joint development IGI
IGI: Inferred from genetic interaction
21262216 MGI
involved in embryonic skeletal joint morphogenesis IGI
IGI: Inferred from genetic interaction
21262216 MGI
involved in embryonic skeletal limb joint morphogenesis IGI
IGI: Inferred from genetic interaction
21262216 MGI
acts upstream of or within gonad development IMP
IMP: Inferred from mutant phenotype
16223478 MGI
acts upstream of or within heart development IMP
IMP: Inferred from mutant phenotype
16223478 MGI
involved in heart development IMP
IMP: Inferred from mutant phenotype
16223478 MGI
acts upstream of or within intermediate mesoderm development IMP
IMP: Inferred from mutant phenotype
16223478 MGI
involved in mesangial cell development IMP
IMP: Inferred from mutant phenotype
18835385 MGI
involved in mesonephric duct morphogenesis IMP
IMP: Inferred from mutant phenotype
16790474 MGI
involved in mesonephros development IMP
IMP: Inferred from mutant phenotype
16790474 MGI
involved in metanephric cap mesenchymal cell proliferation involved in metanephros development IMP
IMP: Inferred from mutant phenotype
18835385 MGI
involved in metanephric epithelium development IMP
IMP: Inferred from mutant phenotype
18835385 MGI
involved in metanephric glomerulus vasculature development IMP
IMP: Inferred from mutant phenotype
18835385 MGI
involved in metanephric interstitial fibroblast development IMP
IMP: Inferred from mutant phenotype
18835385 MGI
involved in metanephric mesenchymal cell differentiation IMP
IMP: Inferred from mutant phenotype
16790474 MGI
involved in metanephric mesenchyme development IDA
IDA: Inferred from direct assay
20171952 MGI
involved in metanephric mesenchyme morphogenesis IMP
IMP: Inferred from mutant phenotype
16790474 MGI
involved in metanephric nephron tubule development IMP
IMP: Inferred from mutant phenotype
18835385 MGI
involved in metanephric smooth muscle tissue development IMP
IMP: Inferred from mutant phenotype
18835385 MGI
acts upstream of or within metanephros development IMP
IMP: Inferred from mutant phenotype
16223478 MGI
involved in middle ear morphogenesis IGI
IGI: Inferred from genetic interaction
19389375 MGI
involved in negative regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
16790474 MGI
involved in negative regulation of epithelial cell differentiation IMP
IMP: Inferred from mutant phenotype
16790474 MGI
involved in negative regulation of nephron tubule epithelial cell differentiation IMP
IMP: Inferred from mutant phenotype
16790474 MGI
involved in negative regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
21262216 MGI
involved in odontogenesis IGI
IGI: Inferred from genetic interaction
19389375 MGI
involved in pattern specification involved in metanephros development IMP
IMP: Inferred from mutant phenotype
18835385 MGI
involved in positive regulation of bone mineralization IGI
IGI: Inferred from genetic interaction
21262216 MGI
involved in positive regulation of epithelial cell proliferation IGI
IGI: Inferred from genetic interaction
19389375 MGI
involved in positive regulation of gene expression IMP
IMP: Inferred from mutant phenotype
16790474 MGI
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
17547533 MGI
involved in positive regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
21262216 MGI
involved in posterior mesonephric tubule development IMP
IMP: Inferred from mutant phenotype
16790474 MGI
involved in renal vesicle progenitor cell differentiation IMP
IMP: Inferred from mutant phenotype
18835385 MGI
involved in roof of mouth development IGI
IGI: Inferred from genetic interaction
19389375 MGI
involved in sodium ion transmembrane transport IMP
IMP: Inferred from mutant phenotype
31736353 MGI
involved in specification of anterior mesonephric tubule identity IMP
IMP: Inferred from mutant phenotype
16790474 MGI
involved in specification of posterior mesonephric tubule identity IMP
IMP: Inferred from mutant phenotype
16790474 MGI
involved in stem cell differentiation IDA
IDA: Inferred from direct assay
20171952 MGI
involved in ureter urothelium development IMP
IMP: Inferred from mutant phenotype
18835385 MGI
involved in ureteric bud development IMP
IMP: Inferred from mutant phenotype
16790474 MGI
involved in urogenital system development IMP
IMP: Inferred from mutant phenotype
16223478 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein odd-skipped-related 1

  • odd-skipped related 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-151545 WNK1-IN-1 Inhibitor 98.67% Unkown
HY-175875 HRZ-01-082-5 Degrader / Unkown
HY-E70807 Biotin-WNK3 Recombinant Human Active Protein Kinase / Unkown
HY-RS09852 OSR1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS09892 OXSR1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18147 Osr1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19467 Oxsr1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24622 Osr1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Osr1 NCBI NCBI:130497