LAMP5 - lysosomal associated membrane protein family member 5 Gene

Homo sapiens

Also known as LAMP-5; UNC-46; BADLAMP; BAD-LAMP; C20orf103

Gene ID: 24141 | Gene type: protein coding

About LAMP5

Cytogenetic location: 20p12.2 Genomic coordinates (GRCh38): 20:9,514,590-9,530,524 (from NCBI)

This gene has 2 transcripts (splice variants), 200 orthologues and 3 paralogues. Biased expression in brain (RPKM 17.1), ovary (RPKM 10.7) and 6 other tissues.

Summary

Predicted to be involved in establishment of protein localization to organelle. Located in endoplasmic reticulum-Golgi intermediate compartment membrane; endosome membrane; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

LAMP5 Products(2)

mRNA	Protein	Name
NM_001199897.2	NP_001186826.1	lysosome-associated membrane glycoprotein 5 isoform 2 precursor
NM_012261.4	NP_036393.1	lysosome-associated membrane glycoprotein 5 isoform 1 precursor

LAMP5 Protein Structure

Lamp

0
100
200
280 a.a.

Protein Preferred Names

Protein Names

lysosome-associated membrane glycoprotein 5

LAMP family protein C20orf103

Recombinant LAMP5 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P77978	LAMP5/BAD-LAMP Protein, Human (HEK293, Fc)	Q9UJQ1 (E30-E235)	≥95%
HY-P700775	LAMP5/BAD-LAMP Protein, Human (HEK293, His)	Q9UJQ1-1 (E30-E235)	≥95%

Related Diseases

Diseases

Alias

Epilepsy, Familial Temporal Lobe, 5

Familial Temporal Lobe Epilepsy 5	ETL5
Epilepsy, Temporal Lobe, Familial, Type 5

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS07512	LAMP5 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	LAMP5	RGD	RGD:1306991
Mus musculus	LAMP5	MGD	MGI:1923411
Canis familiaris	LAMP5	VGNC	VGNC:42576
Bos taurus	LAMP5	VGNC	VGNC:30778
Felis catus	LAMP5	VGNC	VGNC:63188
Macaca mulatta	LAMP5	VGNC	VGNC:74055
Macaca fascicularis	LAMP5	NCBI
Others	LAMP5	NCBI

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