LAMP5 - lysosomal associated membrane protein family member 5 Gene

Also Known as LAMP-5; UNC-46; BADLAMP; BAD-LAMP; C20orf103

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 24141

About LAMP5

Cytogenetic location: 20p12.2 Genomic coordinates (GRCh38): 20:9,514,590-9,530,524 (from NCBI)

This gene has 2 transcripts (splice variants), 200 orthologues and 3 paralogues. Biased expression in brain (RPKM 17.1), ovary (RPKM 10.7) and 6 other tissues.

Summary

Predicted to be involved in establishment of protein localization to organelle. Located in endoplasmic reticulum-Golgi intermediate compartment membrane; endosome membrane; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

LAMP5 Products (2)

mRNA Protein Name
NM_001199897.2 NP_001186826.1 lysosome-associated membrane glycoprotein 5 isoform 2 precursor
NM_012261.4 NP_036393.1 lysosome-associated membrane glycoprotein 5 isoform 1 precursor

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum-Golgi intermediate compartment membrane IDA
IDA: Inferred from direct assay
21642595 GOA
located in endosome membrane IDA
IDA: Inferred from direct assay
21642595 GOA
located in plasma membrane IDA
IDA: Inferred from direct assay
21642595 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

LAMP5 Protein Structure

Lamp

Lamp: Lysosome-associated membrane glycoprotein (Lamp) (42 - 263)

  • 0
  • 100
  • 200
  • 280 a.a.
Protein Preferred Names Protein Names

lysosome-associated membrane glycoprotein 5

  • LAMP family protein C20orf103

Recombinant LAMP5 Proteins

Cat. No. Product Name Accession Purity
HY-P77978 LAMP5/BAD-LAMP Protein, Human (HEK293, Fc) Q9UJQ1-1 (E30-E235) ≥ 95%, as determined by Bis-Tris PAGE.
HY-P700775 LAMP5/BAD-LAMP Protein, Human (HEK293, His) Q9UJQ1-1 (E30-E235) ≥ 95%, as determined by reducing SDS-PAGE.

Related Diseases

Diseases Alias
Epilepsy, Familial Temporal Lobe, 5

  • Familial Temporal Lobe Epilepsy 5

  • ETL5

  • Epilepsy, Temporal Lobe, Familial, Type 5
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS07512 LAMP5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18531 Lamp5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25013 Lamp5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus LAMP5 RGD RGD:1306991
Mus musculus LAMP5 MGD MGI:1923411
Canis familiaris LAMP5 VGNC VGNC:42576
Bos taurus LAMP5 VGNC VGNC:30778
Felis catus LAMP5 VGNC VGNC:63188
Macaca mulatta LAMP5 VGNC VGNC:74055
Others LAMP5 NCBI