Ets1 - ETS proto-oncogene 1, transcription factor Gene

Also Known as Tpl1; Ets-1; Etsoncb

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24356

Summary

Enables Histone Acetyltransferase binding activity and sequence-specific DNA binding activity. Involved in several processes, including angiogenesis involved in wound healing; diencephalon development; and estrous cycle. Located in nucleus. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human ETS1 (ETS proto-oncogene 1, transcription factor). [provided by Alliance of Genome Resources, Apr 2022]

Ets1 Products (1)

mRNA Protein Name
NM_012555.2 NP_036687.1 protein C-ets-1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables histone acetyltransferase binding IPI
IPI: Inferred from physical interaction
22357921 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
12145332 RGD
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
8635216 RGD
Biological Process GO Annotation Evidence References Source
involved in angiogenesis involved in wound healing IEP
IEP: Inferred from expression pattern
9600079 RGD
involved in cellular response to hydrogen peroxide IEP
IEP: Inferred from expression pattern
16192649 RGD
involved in estrous cycle IEP
IEP: Inferred from expression pattern
18439600 RGD
involved in female pregnancy IEP
IEP: Inferred from expression pattern
18439600 RGD
involved in hypothalamus development IEP
IEP: Inferred from expression pattern
8946059 RGD
involved in pituitary gland development IEP
IEP: Inferred from expression pattern
8946059 RGD
involved in positive regulation of angiogenesis IMP
IMP: Inferred from mutant phenotype
12725417 RGD
involved in positive regulation of cell migration IMP
IMP: Inferred from mutant phenotype
19148472 RGD
involved in positive regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
15806297 RGD
involved in regulation of extracellular matrix disassembly IMP
IMP: Inferred from mutant phenotype
16738537 RGD
involved in response to estradiol IEP
IEP: Inferred from expression pattern
12725417 RGD
involved in response to hypoxia IEP
IEP: Inferred from expression pattern
15579511 RGD
involved in response to interleukin-1 IEP
IEP: Inferred from expression pattern
16046515 RGD
involved in response to laminar fluid shear stress IEP
IEP: Inferred from expression pattern
18636553 RGD
involved in response to mechanical stimulus IEP
IEP: Inferred from expression pattern
18272346 RGD
involved in response to salt IEP
IEP: Inferred from expression pattern
31932071 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein C-ets-1

  • Ets avian erythroblastosis virus E2 oncogene homolog 1 (tumor progression locus 1)

  • p54

  • v-ets avian erythroblastosis virus E26 oncogene homolog 1

  • v-ets erythroblastosis virus E26 oncogene homolog 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-W002199 6:2 Fluorotelomer alcohol 99.96% Unkown
HY-RS04562 ETS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16879 Ets1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23321 Ets1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28129 Kcnh8 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ets1 NCBI NCBI:2113