Grm3 - glutamate metabotropic receptor 3 Gene

Also Known as mGluR3

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24416

About Grm3

Primary_assembly 4: 24,365,115-24,609,804 forward strand.mRatBN7.2:CM026977.1

This gene has 3 transcripts (splice variants), 215 orthologues, 7 paralogues and is associated with 5 phenotypes. Restricted expression toward (RPKM 261.3).

Summary

Enables group II metabotropic glutamate receptor activity and scaffold protein binding activity. Involved in modulation of chemical synaptic transmission. Located in astrocyte projection and axon. Orthologous to human GRM3 (glutamate metabotropic receptor 3). [provided by Alliance of Genome Resources, Apr 2022]

Grm3 Products (1)

mRNA Protein Name
NM_001105712.1 NP_001099182.1 metabotropic glutamate receptor 3 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables group II metabotropic glutamate receptor activity IMP
IMP: Inferred from mutant phenotype
12694929 RGD
enables scaffold protein binding IPI
IPI: Inferred from physical interaction
28392297 RGD
Biological Process GO Annotation Evidence References Source
involved in modulation of chemical synaptic transmission IDA
IDA: Inferred from direct assay
12694929 RGD
Cellular Component GO Annotation Evidence References Source
located in astrocyte projection IDA
IDA: Inferred from direct assay
21753079 RGD
located in axon IDA
IDA: Inferred from direct assay
28392297 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Grm3 Protein Structure

PBP1_mGluR_groupII

PBP1_mGluR_groupII: cd06375 (32 - 493)

NCD3G

NCD3G: pfam07562 (504 - 554)

7tmC_mGluR3

7tmC_mGluR3: cd15448 (574 - 827)

7tmC_mGluR3

7tmC_mGluR3: cd15448 (574 - 599)

7tmC_mGluR3

7tmC_mGluR3: cd15448 (611 - 632)

7tmC_mGluR3

7tmC_mGluR3: cd15448 (641 - 665)

7tmC_mGluR3

7tmC_mGluR3: cd15448 (687 - 707)

7tmC_mGluR3

7tmC_mGluR3: cd15448 (732 - 758)

7tmC_mGluR3

7tmC_mGluR3: cd15448 (766 - 789)

7tmC_mGluR3

7tmC_mGluR3: cd15448 (796 - 821)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 903 a.a.
Protein Preferred Names Protein Names

metabotropic glutamate receptor 3

  • glutamate receptor, metabotropic 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05825 GRM3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05826 Grm3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05827 Grm3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Grm3 NCBI NCBI:2913