Cnksr2 - connector enhancer of kinase suppressor of Ras 2 Gene

Also Known as Cnk2; Ksr2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 245684

Summary

Predicted to enable identical protein binding activity and protein kinase binding activity. Predicted to be involved in postsynapse organization. Predicted to act upstream of or within intracellular signal transduction. Located in postsynaptic density. Human ortholog(s) of this gene implicated in syndromic X-linked mental retardation Hough type. Orthologous to human CNKSR2 (connector enhancer of kinase suppressor of Ras 2). [provided by Alliance of Genome Resources, Apr 2022]

Cnksr2 Products (3)

mRNA Protein Name
NM_001310719.1 NP_001297648.1 connector enhancer of kinase suppressor of ras 2 isoform 2
NM_001374835.1 NP_001361764.1 connector enhancer of kinase suppressor of ras 2 isoform 3
NM_177751.3 NP_808419.1 connector enhancer of kinase suppressor of ras 2 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
28671696 MGI
Biological Process GO Annotation Evidence References Source
involved in postsynaptic specialization organization IDA
IDA: Inferred from direct assay
36803960 MGI
involved in postsynaptic specialization organization IMP
IMP: Inferred from mutant phenotype
36803960 MGI
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
36803960 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
36803960 MGI
located in postsynaptic density IDA
IDA: Inferred from direct assay
17114649 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

connector enhancer of kinase suppressor of ras 2

  • CNK homolog protein 2

  • connector enhancer of KSR 2

  • connector enhancer of KSR2

Cnksr2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Cnksr2 Q80YA9 Dlgap1 Mus musculus Q9D415
Anti Bait CoIP
28671696
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS02889 CNKSR2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cnksr2 NCBI NCBI:22866