MUC2 - Muc2 mucin 2, oligomeric mucus/gel-forming Gene

Also Known as MLP; HH-Muc; AABR07006030.1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24572

Summary

Enables identical protein binding activity. Involved in several processes, including cellular response to tumor necrosis factor; response to lipopolysaccharide; and response to vitamin A. Located in cytoplasm; mucus layer; and nucleus. Used to study colitis; intestinal disease; and pneumonia. Biomarker of several diseases, including colitis (multiple); colon cancer; liver cirrhosis; mucositis; and perinatal necrotizing enterocolitis. Human ortholog(s) of this gene implicated in asthma. Orthologous to human MUC2 (Mucin 2, oligomeric mucus/gel-forming). [provided by Alliance of Genome Resources, Apr 2022]

MUC2 Products (1)

mRNA Protein Name
XM_039101270.1 XP_038957198.1 mucin-2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables identical protein binding IMP
IMP: Inferred from mutant phenotype
12744721 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
21629776 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to tumor necrosis factor IEP
IEP: Inferred from expression pattern
18507686 RGD
involved in response to Gram-positive bacterium IEP
IEP: Inferred from expression pattern
20501441 RGD
involved in response to hormone IEP
IEP: Inferred from expression pattern
17495032 RGD
involved in response to lipopolysaccharide IEP
IEP: Inferred from expression pattern
17417665 RGD
involved in response to transforming growth factor beta IEP
IEP: Inferred from expression pattern
15980276 RGD
involved in response to vitamin A IEP
IEP: Inferred from expression pattern
18495461 RGD
Cellular Component GO Annotation Evidence References Source
located in mucus layer IDA
IDA: Inferred from direct assay
21629776 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mucin-2

  • MUC-2

  • intestinal mucin-2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-E70562 Mucinase StcE Activator / Unkown
HY-158471 Core 1 O-glycan (C1) / Unkown
HY-RS08838 MUC2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18623 Muc2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25109 Muc2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens MUC2 NCBI NCBI:4583