Npr1 - natriuretic peptide receptor 1 Gene

Also Known as Gca; Npra; Anpra; NPR-A

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24603

Summary

Enables Guanylate Cyclase activity. Involved in several processes, including cGMP-mediated signaling; negative regulation of smooth muscle cell proliferation; and positive regulation of cGMP-mediated signaling. Located in plasma membrane. Used to study hypertension. Human ortholog(s) of this gene implicated in myocardial infarction. Orthologous to human NPR1 (natriuretic peptide receptor 1). [provided by Alliance of Genome Resources, Apr 2022]

Npr1 Products (1)

mRNA Protein Name
NM_012613.1 NP_036745.1 atrial natriuretic peptide receptor 1 precursor
Protein Preferred Names Protein Names

atrial natriuretic peptide receptor 1

  • ANP-A

  • ANPR-A

  • GC-A

  • atrial natriuretic peptide A-type receptor

  • atrial natriuretic peptide receptor A

  • atrial natriuretic peptide receptor type A

  • guanylate cyclase A

  • natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P990921 Imelciment / Phase 1

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P1419 AP 811 Antagonist 99.64% Unkown
HY-153650 JS11 Inhibitor 99.22% Unkown
HY-177062 NPRA agonist-11 Agonist / Unkown
HY-P1419A AP 811 acetate Antagonist / Unkown
HY-RS09497 NPR1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18627 Npr1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25113 Npr1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P990951 Vixticibart Agonist 97.83% Unkown
HY-P991121 Baloncibart Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Npr1 NCBI NCBI:4881