Tubb3 - tubulin, beta 3 class III Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 246118

Summary

Enables peptide binding activity. Involved in mitotic cell cycle and neuron differentiation. Located in axon. Human ortholog(s) of this gene implicated in complex cortical dysplasia with Other brain malformations 1 and congenital fibrosis of the extraocular muscles 3A. Orthologous to human TUBB3 (tubulin beta 3 class III). [provided by Alliance of Genome Resources, Apr 2022]

Tubb3 Products (1)

mRNA Protein Name
NM_139254.2 NP_640347.2 tubulin beta-3 chain

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables peptide binding IPI
IPI: Inferred from physical interaction
16893427 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
24882364 RGD
Biological Process GO Annotation Evidence References Source
involved in neuron differentiation IMP
IMP: Inferred from mutant phenotype
12234689 RGD
Cellular Component GO Annotation Evidence References Source
located in axon IDA
IDA: Inferred from direct assay
12368262 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tubulin beta-3 chain

  • neuron-specific class III beta-tubulin

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-158208 PMMB276 Inhibitor 99.81% Unkown
HY-158208A (1S)-PMMB276 Control / Unkown
HY-RS15254 TUBB3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19491 Tubb3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25985 Tubb3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tubb3 NCBI NCBI:10381