2. Apoptosis
  3. Apoptosis
  4. PMMB276

PMMB276 is a potent inhibitor of β-tubulin isotype III (Tubb3) polymerization and induced apoptosis. PMMB276 plays an important role in cancer research.

For research use only. We do not sell to patients.

PMMB276

PMMB276 Chemical Structure

CAS No. : 2209036-28-0

Size Price Stock Quantity
5 mg Get quote 7 - 9 weeks 6 - 8 weeks 8 - 10 weeks 6 - 8 weeks
10 mg Get quote 7 - 9 weeks 6 - 8 weeks 8 - 10 weeks 6 - 8 weeks
25 mg Get quote 7 - 9 weeks 6 - 8 weeks 8 - 10 weeks 6 - 8 weeks
50 mg Get quote 7 - 9 weeks 6 - 8 weeks 8 - 10 weeks 6 - 8 weeks
100 mg Get quote 7 - 9 weeks 6 - 8 weeks 8 - 10 weeks 6 - 8 weeks
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Based on 1 publication(s) in Google Scholar

Other Forms of PMMB276:

PMMB276 Related Antibodies

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Description

PMMB276 is a potent inhibitor of β-tubulin isotype III (Tubb3) polymerization and induced apoptosis. PMMB276 plays an important role in cancer research[1].

Cellular Effect
Cell Line Type Value Description References
A549 IC50
16.37 μM
Compound: 1c
Antiproliferative activity against human A549 cells after 24 hrs by MTT assay
Antiproliferative activity against human A549 cells after 24 hrs by MTT assay
[PMID: 29268130]
HEK-293T IC50
88.83 μM
Compound: 1c
Antiproliferative activity against human 293T cells after 24 hrs by MTT assay
Antiproliferative activity against human 293T cells after 24 hrs by MTT assay
[PMID: 29268130]
HeLa IC50
3.14 μM
Compound: 1c
Antiproliferative activity against human HeLa cells after 24 hrs by MTT assay
Antiproliferative activity against human HeLa cells after 24 hrs by MTT assay
[PMID: 29268130]
HepG2 IC50
5.37 μM
Compound: 1c
Antiproliferative activity against human HepG2 cells after 24 hrs by MTT assay
Antiproliferative activity against human HepG2 cells after 24 hrs by MTT assay
[PMID: 29268130]
L02 IC50
116.2 μM
Compound: 1c
Antiproliferative activity against human LO2 cells after 24 hrs by MTT assay
Antiproliferative activity against human LO2 cells after 24 hrs by MTT assay
[PMID: 29268130]
MDA-MB-231 IC50
17.67 μM
Compound: 1c
Antiproliferative activity against human MDA231 cells after 24 hrs by MTT assay
Antiproliferative activity against human MDA231 cells after 24 hrs by MTT assay
[PMID: 29268130]
Molecular Weight

566.73

Formula

C31H34O6S2
CAS No.
Appearance

Solid

Color

Brown to reddish brown

SMILES

O=C(C1=C(C=CC(O)=C12)O)C=C([C@@H](C/C=C(C)/C)OC(CCCC[C@H]3SC(SCC3)C4=CC=CC=C4)=O)C2=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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PMMB276 Related Classifications

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PMMB2762209036-28-0PMMB 276PMMB-276Apoptosistriple-negative breast cancer，Inhibitorinhibitorinhibit

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