ATRX - Atrx ATRX, chromatin remodeler Gene

Also Known as Xnp

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 246284

Summary

Predicted to enable several functions, including DNA translocase activity; chromo shadow domain binding activity; and methylated histone binding activity. Predicted to be involved in several processes, including chromatin assembly; regulation of chromosome organization; and regulation of telomeric RNA transcription from RNA pol II promoter. Predicted to act upstream of or within several processes, including male gonad development; meiotic spindle organization; and post-embryonic forelimb morphogenesis. Located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in X-linked mental retardation-hypotonic facies syndrome-1; alpha thalassemia-X-linked intellectual disability syndrome; alpha-thalassemia myelodysplasia syndrome; high grade glioma; and lung small cell carcinoma. Orthologous to human ATRX (ATRX chromatin remodeler). [provided by Alliance of Genome Resources, Apr 2022]

ATRX Products (1)

mRNA Protein Name
NM_001105757.2 NP_001099227.2 transcriptional regulator ATRX

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
8667030 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcriptional regulator ATRX

  • ATP-dependent helicase ATRX

  • X-linked nuclear protein

  • helicase II

  • pABP-2

  • transcriptional regulator ATRX-like

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01252 ATRX Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19577 Atrx Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26074 Atrx Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens ATRX NCBI NCBI:546