Tradd - TNFRSF1A-associated via death domain Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 246756

Summary

Enables tumor necrosis factor receptor binding activity. Predicted to be involved in several processes, including cellular response to tumor necrosis factor; positive regulation of NF-kappaB transcription factor activity; and positive regulation of intracellular signal transduction. Located in membrane raft. Part of protein-containing complex. Orthologous to human TRADD (TNFRSF1A associated via death domain). [provided by Alliance of Genome Resources, Apr 2022]

Tradd Products (1)

mRNA Protein Name
NM_001100480.1 NP_001093950.1 tumor necrosis factor receptor type 1-associated DEATH domain protein

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
12786973 RGD
enables protein-containing complex binding IPI
IPI: Inferred from physical interaction
12786973 RGD
enables tumor necrosis factor receptor binding IPI
IPI: Inferred from physical interaction
20649583 RGD
Cellular Component GO Annotation Evidence References Source
part of protein-containing complex IDA
IDA: Inferred from direct assay
12786973 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tumor necrosis factor receptor type 1-associated DEATH domain protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-134050 Apostatin-1 99.64% Unkown
HY-138779 ICCB-19 hydrochloride 99.25% Unkown
HY-114573 TNF-α-IN-19 Inhibitor / Unkown
HY-RS14966 TRADD Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17209 Tradd Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23661 Tradd Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tradd NCBI NCBI:8717