2. Gene
  3. Rara - retinoic acid receptor, alpha Gene

Rara - retinoic acid receptor, alpha Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 24705 | Gene type: protein coding

About Rara

Primary_assembly 10: 83,893,384-83,928,142 forward strand.mRatBN7.2:CM026983.1

This gene has 2 transcripts (splice variants), 331 orthologues, 19 paralogues and is associated with 12 phenotypes. Biased expression in Lung (RPKM 12.3), Kidney (RPKM 75.) and 9 other tissues.

Summary

Enables histone deacetylase binding activity; nucleic acid binding activity; and phosphatidylinositol 3-kinase regulator activity. Involved in several processes, including animal organ development; positive regulation of intracellular signal transduction; and response to vitamin A. Located in dendrite; nucleus; and perinuclear region of cytoplasm. Biomarker of amyotrophic lateral sclerosis. Human ortholog(s) of this gene implicated in acute promyelocytic leukemia. Orthologous to human RARA (retinoic acid receptor alpha). [provided by Alliance of Genome Resources, Apr 2022]

Rara Products(1)

mRNA Protein Name
NM_031528.2 NP_113716.2 retinoic acid receptor alpha

Rara Protein Structure

NR_DBD_RAR

NR_DBD_RAR: cd06964 (81 - 165)

NR_LBD_RAR

NR_LBD_RAR: cd06937 (185 - 415)

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  • 462 a.a.
Protein Preferred Names Protein Names

retinoic acid receptor alpha

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-101106 AR7 Antagonist 98.85% Unkown
HY-RS11669 RARA Human Pre-designed siRNA Set A / Unkown
HY-RS11670 Rara Mouse Pre-designed siRNA Set A / Unkown
HY-RS11671 Rara Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rara NCBI NCBI:5914