Sct - secretin Gene

Also Known as Secr

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24769

Summary

Enables digestive hormone activity and protein N-terminus binding activity. Involved in several processes, including cellular water homeostasis; positive regulation of cAMP-mediated signaling; and regulation of secretion. Located in extracellular space. Orthologous to human SCT (secretin). [provided by Alliance of Genome Resources, Apr 2022]

Sct Products (1)

mRNA Protein Name
NM_022670.3 NP_073161.1 secretin precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables digestive hormone activity IDA
IDA: Inferred from direct assay
3047699 RGD
enables hormone activity IDA
IDA: Inferred from direct assay
19805236 RGD
Biological Process GO Annotation Evidence References Source
involved in embryonic digestive tract development IEP
IEP: Inferred from expression pattern
1711228 RGD
involved in intracellular water homeostasis IDA
IDA: Inferred from direct assay
19805236 RGD
involved in negative regulation of gastrin-induced gastric acid secretion IDA
IDA: Inferred from direct assay
11123201 RGD
involved in positive regulation of cAMP/PKA signal transduction IDA
IDA: Inferred from direct assay
12403838 RGD
involved in positive regulation of pancreatic juice secretion IDA
IDA: Inferred from direct assay
11123201 RGD
involved in positive regulation of somatostatin secretion IDA
IDA: Inferred from direct assay
11123201 RGD
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
3047699 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

secretin

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (4)
Cat. No. Product Name Effect
Purity Phase
HY-P99769 Omfiloctocog alfa 97.10% Phase 4
HY-P99952 Ripertamab Inhibitor ≥99.0% Phase 3
HY-P99619 Finotonlimab Inhibitor 97.50% Phase 3
HY-P991507 SCT200 Inhibitor 99.09% Phase 2

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-179321 PROTAC HDAC4 Degrader-1 Degrader / Unkown
HY-RS04980 FLNB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12567 SCT Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19113 Sct Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25603 Sct Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P991035 Turenkibart Inhibitor 99.12% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sct NCBI NCBI:6343