CTH - Cth cystathionine gamma-lyase Gene

Also Known as CGL; CSE

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 24962

Summary

Enables cystathionine beta-lyase activity. Involved in several processes, including alpha-amino acid metabolic process; glutathione metabolic process; and negative regulation of cell growth. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Used to study cataract. Human ortholog(s) of this gene implicated in amino acid metabolic disorder and cystathioninuria. Orthologous to human CTH (cystathionine gamma-lyase). [provided by Alliance of Genome Resources, Apr 2022]

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in glutathione metabolic process IMP
IMP: Inferred from mutant phenotype
15683713 RGD
involved in negative regulation of cell growth IMP
IMP: Inferred from mutant phenotype
15347670 RGD
involved in negative regulation of cell population proliferation IMP
IMP: Inferred from mutant phenotype
15347670 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cystathionine gamma-lyase

  • CTL target antigen

  • PRB-RA

  • cystathionase (cystathionine gamma-lyase)

  • cysteine desulfhydrase

  • cysteine-protein sulfhydrase

  • gamma-cystathionase

  • homocysteine desulfhydrase

  • probasin-related antigen

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03296 CTH Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-181717 TKL002 98.08% Unkown
HY-RS15708 VSIG2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17261 Cth Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23715 Cth Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens CTH NCBI NCBI:1491