Gpd2 - glycerol-3-phosphate dehydrogenase 2 Gene

Also Known as mtGPDH

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25062

Summary

Enables glycerol-3-phosphate dehydrogenase [NAD+] activity. Involved in NADH metabolic process and glycerol-3-phosphate metabolic process. Predicted to be part of glycerol-3-phosphate dehydrogenase complex. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human GPD2 (glycerol-3-phosphate dehydrogenase 2). [provided by Alliance of Genome Resources, Apr 2022]

Gpd2 Products (1)

mRNA Protein Name
NM_012736.2 NP_036868.1 glycerol-3-phosphate dehydrogenase, mitochondrial precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in NADH metabolic process IDA
IDA: Inferred from direct assay
12351438 RGD
involved in glycerol-3-phosphate metabolic process IDA
IDA: Inferred from direct assay
12351438 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glycerol-3-phosphate dehydrogenase, mitochondrial

  • GPD-M

  • GPDH-M

  • Glycerol-3-phosophate dehydrogenase 2 (mitochondrial)

  • glycerol-3-phosphate dehydrogenase 2, mitochondrial

  • mtGPDH gene, promoter region and alternative transcripts

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-148685 KM04416 Inhibitor 98.76% Unkown
HY-RS05635 GPD2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17954 Gpd2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24425 Gpd2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gpd2 NCBI NCBI:2820