Sry - sex determining region Y Gene

Also Known as Tdf; Tdy; Sry1; Sry3; Sry3B; Sry3C; Sry3BI; SRYGENE

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25221

Summary

Enables enzyme binding activity and sequence-specific DNA binding activity. Involved in male sex determination and positive regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in 46,XX sex reversal 1; 46,XY sex reversal; and 46,XY sex reversal 1. Orthologous to human SRY (sex determining region Y). [provided by Alliance of Genome Resources, Apr 2022]

Sry Products (1)

mRNA Protein Name
NM_012772.1 NP_036904.1 sex-determining region Y protein

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables enzyme binding IPI
IPI: Inferred from physical interaction
16904257 RGD
enables sequence-specific DNA binding IMP
IMP: Inferred from mutant phenotype
15464265 RGD
Biological Process GO Annotation Evidence References Source
involved in male sex determination IEP
IEP: Inferred from expression pattern
8430080 RGD
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
15464265 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sex-determining region Y protein

  • HMG box transcription factor Sry1

  • HMG box transcription factor Sry3

  • HMG box transcription factor Sry3B

  • HMG box transcription factor Sry3BI

  • HMG box transcription factor Sry3C

  • Testis determining locus

  • sex determining region of Chr Y

  • sex determining r

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13801 SRY Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174539 Human SOX2 mRNA / Unkown
HY-RS21288 Sry Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23830 Sox9 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27807 Sry Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sry NCBI NCBI:6736