Coq7 - coenzyme Q7, hydroxylase Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25249

Summary

Predicted to enable 2-octoprenyl-3-methyl-6-methoxy-1,4-benzoquinone hydroxylase activity and chromatin binding activity. Involved in response to xenobiotic stimulus and ubiquinone biosynthetic process. Predicted to be located in mitochondrion. Predicted to be active in mitochondrial inner membrane and nucleus. Human ortholog(s) of this gene implicated in primary coenzyme Q10 deficiency 8. Orthologous to human COQ7 (coenzyme Q7, hydroxylase). [provided by Alliance of Genome Resources, Apr 2022]

Coq7 Products (1)

mRNA Protein Name
NM_012785.3 NP_036917.2 5-demethoxyubiquinone hydroxylase, mitochondrial

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
16595124 RGD
involved in ubiquinone biosynthetic process IGI
IGI: Inferred from genetic interaction
8660658 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

5-demethoxyubiquinone hydroxylase, mitochondrial

  • Coenzyme q (ubiquinone) biosynthetic enzyme (DHPB methyltransferase) 7

  • DMQ hydroxylase

  • coenzyme Q biosynthesis protein 7 homolog

  • coenzyme Q7 homolog, ubiquinone

  • demethyl-Q 7

  • timing protein clk-1 homolog

  • ubiquinone biosynthesis monooxygenase COQ7

  • ub

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-133033 COQ7-IN-1 Inhibitor 99.55% Unkown
HY-138429 COQ7-IN-2 Inhibitor 99.74% Unkown
HY-RS03043 COQ7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18468 Coq7 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24949 Coq7 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Coq7 NCBI NCBI:10229