Cort - cortistatin Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25305

Summary

Enables neuropeptide hormone activity. Involved in neuropeptide signaling pathway and regulation of circadian sleep/wake cycle, sleep. Predicted to be located in extracellular region. Orthologous to human CORT (cortistatin). [provided by Alliance of Genome Resources, Apr 2022]

Cort Products (1)

mRNA Protein Name
NM_012835.1 NP_036967.1 cortistatin preproprotein

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables neuropeptide hormone activity IDA
IDA: Inferred from direct assay
11817718 RGD
Biological Process GO Annotation Evidence References Source
involved in neuropeptide signaling pathway IDA
IDA: Inferred from direct assay
11817718 RGD
involved in regulation of circadian sleep/wake cycle, sleep IDA
IDA: Inferred from direct assay
8622767 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cortistatin

  • Preprocortistatin

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Phase
HY-117880 Exicorilant Antagonist 99.48% Phase 2
HY-15710 Cort108297 Antagonist 99.80% Phase 2
HY-132811 Dazucorilant Modulator 98.91% Phase 2
HY-117965 Miricorilant / Phase 2

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03054 CORT Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16810 Cort Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23250 Cort Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cort NCBI NCBI:1325