Oxtr - oxytocin receptor Gene

Rattus norvegicus

Also known as OTR; OT-R; OTR1

Gene ID: 25342 | Gene type: protein coding

About Oxtr

Primary_assembly 4: 145,599,561-145,614,674 reverse strand.mRatBN7.2:CM026977.1

This gene has 1 transcript (splice variant), 265 orthologues, 16 paralogues and is associated with 25 phenotypes. Biased expression in Adrenal (RPKM 17.2), Uterus (RPKM 11.7) and 7 other tissues.

Summary

Enables Oxytocin Receptor activity and peptide hormone binding activity. Involved in several processes, including ERK1 and ERK2 cascade; positive regulation of synaptic transmission; and regulation of secretion. Located in adherens junction; apical plasma membrane; and microvillus. Used to study gastric ulcer. Biomarker of hypertension. Orthologous to human OXTR (Oxytocin Receptor). [provided by Alliance of Genome Resources, Apr 2022]

Oxtr Products(1)

mRNA	Protein	Name
NM_012871.4	NP_037003.2	oxytocin receptor

Oxtr Protein Structure

7tmA_OT_R

0
100
200
300
388 a.a.

Protein Preferred Names

Protein Names

oxytocin receptor

oxcytocin receptor

Related Agents

Pre-clinical Phase

Bioactive Molecules (7)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-108678	TC OT 39		/	Unkown
HY-P4990	Pro8-Oxytocin	Activator	/	Unkown
HY-P4990A	Pro8-Oxytocin TFA	Activator	/	Unkown
HY-P5017	(Val3,Pro8)-Oxytocin	Agonist	/	Unkown
HY-RS09894	OXTR Human Pre-designed siRNA Set A		/	Unkown
HY-RS09895	Oxtr Mouse Pre-designed siRNA Set A		/	Unkown
HY-RS09896	Oxtr Rat Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Oxtr	NCBI	NCBI:5021

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