Ctsh - cathepsin H Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25425

Summary

Enables Aminopeptidase activity; kininogen binding activity; and protein self-association. Involved in several processes, including cellular response to thyroid hormone stimulus; response to odorant; and spermatogenesis. Located in several cellular components, including cytoskeleton; lysosome; and secretory granule. Biomarker of polycystic kidney disease. Orthologous to human CTSH (Cathepsin H). [provided by Alliance of Genome Resources, Apr 2022]

Ctsh Products (1)

mRNA Protein Name
NM_012939.2 NP_037071.1 pro-cathepsin H precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables aminopeptidase activity IDA
IDA: Inferred from direct assay
1483460 RGD
enables identical protein binding IDA
IDA: Inferred from direct assay
7550115 RGD
enables kininogen binding IPI
IPI: Inferred from physical interaction
3356189 RGD
enables protein-containing complex binding IPI
IPI: Inferred from physical interaction
2470410 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to thyroid hormone stimulus IEP
IEP: Inferred from expression pattern
21217776 RGD
involved in metanephros development IEP
IEP: Inferred from expression pattern
16153003 RGD
involved in response to odorant IEP
IEP: Inferred from expression pattern
23103411 RGD
involved in spermatogenesis IEP
IEP: Inferred from expression pattern
9238520 RGD
Cellular Component GO Annotation Evidence References Source
located in acrosomal vesicle IDA
IDA: Inferred from direct assay
12838426 RGD
located in alveolar lamellar body IDA
IDA: Inferred from direct assay
2005374 RGD
located in axoneme IDA
IDA: Inferred from direct assay
12838426 RGD
located in extracellular space IDA
IDA: Inferred from direct assay
2005374 RGD
located in outer dense fiber IDA
IDA: Inferred from direct assay
12838426 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

pro-cathepsin H

  • cathepsin B3

  • cathepsin BA

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS18235 Ctsh Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03336 CTSH Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24714 Ctsh Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ctsh NCBI NCBI:1512