Vps35 - VPS35 retromer complex component Gene

Also Known as Mem3

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25479

Summary

Predicted to enable D1 Dopamine Receptor binding activity. Involved in retrograde transport, endosome to Golgi. Located in cytosol. Part of retromer complex. Human ortholog(s) of this gene implicated in Parkinson's disease and Parkinson's disease 17. Orthologous to human VPS35 (VPS35 retromer complex component). [provided by Alliance of Genome Resources, Apr 2022]

Vps35 Products (1)

mRNA Protein Name
NM_001105718.2 NP_001099188.2 vacuolar protein sorting-associated protein 35

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in retrograde transport, endosome to Golgi IMP
IMP: Inferred from mutant phenotype
23395371 RGD
Cellular Component GO Annotation Evidence References Source
located in cytosol IDA
IDA: Inferred from direct assay
11102511 RGD
part of retromer complex IDA
IDA: Inferred from direct assay
11102511 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

vacuolar protein sorting-associated protein 35

  • Maternal embryonic message 3

  • vacuolar protein sorting 35 homolog

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P11345 VPS35 c-terminal peptide 97.75% Unkown
HY-RS15685 VPS35 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15686 VPS35L Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21083 Vps35 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27600 Vps35 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Vps35 NCBI NCBI:55737