SUN3 - Sad1 and UNC84 domain containing 3 Gene

Also Known as SUNC1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 256979

About SUN3

Cytogenetic location: 7p12.3 Genomic coordinates (GRCh38): 7:47,987,148-48,035,902 (from NCBI)

This gene has 9 transcripts (splice variants), 117 orthologues and 4 paralogues. Restricted expression toward testis (RPKM 18.0).

Summary

Predicted to enable protein-membrane adaptor activity. Predicted to be involved in nuclear envelope organization. Predicted to be integral component of nuclear inner membrane. Predicted to be part of meiotic nuclear membrane microtubule tethering complex. Predicted to be active in nuclear envelope. [provided by Alliance of Genome Resources, Apr 2022]

SUN3 Products (3)

mRNA Protein Name
NM_001030019.2 NP_001025190.1 SUN domain-containing protein 3 isoform 1
NM_001284350.2 NP_001271279.1 SUN domain-containing protein 3 isoform 2
NM_152782.4 NP_689995.3 SUN domain-containing protein 3 isoform 1

SUN3 Protein Structure

Sad1_UNC

Sad1_UNC: Sad1 / UNC-like C-terminal (221 - 352)

  • 0
  • 100
  • 200
  • 300
  • 357 a.a.
Protein Preferred Names Protein Names

SUN domain-containing protein 3

  • Sad1 and UNC84 domain containing 1

Related Diseases

Diseases Alias
Deafness, Autosomal Recessive 40

  • DFNB40

  • Autosomal Recessive Nonsyndromic Deafness 40

  • Autosomal Recessive Deafness 40
Deafness, Autosomal Recessive 55

  • DFNB55

  • Autosomal Recessive Nonsyndromic Deafness 55

  • Autosomal Recessive Deafness 55
Spermatogenic Failure 9

  • Male Infertility Due To Globozoospermia

  • SPGF9

  • Male Infertility Due To Round-Headed Spermatozoa

  • Globozoospermia, Complete

  • Globozoospermia, Total

  • Globozoospermia

  • Globozoospermia Syndrome

  • Round-Headed Sperm Syndrome

  • Globozoospermia Complete

  • Globozoospermia Total
Urocanase Deficiency

  • Encephalopathy Due To Urocanase Deficiency

  • Urocanate Hydratase Deficiency

  • Urocanic Aciduria

  • UROCD

  • High Urine Urocanic Acid Levels
Male Infertility Due To Acephalic Spermatozoa

  • Acephalic Spermatozoa Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14031 SUN3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta SUN3 VGNC VGNC:81768
Mus musculus SUN3 MGD MGI:3041199
Rattus norvegicus SUN3 RGD RGD:1591975
Bos taurus SUN3 VGNC VGNC:35475
Felis catus SUN3 VGNC VGNC:65843
Canis familiaris SUN3 VGNC VGNC:46986
Others SUN3 NCBI