SUN3 - Sad1 and UNC84 domain containing 3 Gene

Homo sapiens

Also known as SUNC1

Gene ID: 256979 | Gene type: protein coding

About SUN3

Cytogenetic location: 7p12.3 Genomic coordinates (GRCh38): 7:47,987,148-48,035,902 (from NCBI)

This gene has 9 transcripts (splice variants), 117 orthologues and 4 paralogues. Restricted expression toward testis (RPKM 18.0).

Summary

Predicted to enable protein-membrane adaptor activity. Predicted to be involved in nuclear envelope organization. Predicted to be integral component of nuclear inner membrane. Predicted to be part of meiotic nuclear membrane microtubule tethering complex. Predicted to be active in nuclear envelope. [provided by Alliance of Genome Resources, Apr 2022]

SUN3 Products(3)

mRNA	Protein	Name
NM_001030019.2	NP_001025190.1	SUN domain-containing protein 3 isoform 1
NM_001284350.2	NP_001271279.1	SUN domain-containing protein 3 isoform 2
NM_152782.4	NP_689995.3	SUN domain-containing protein 3 isoform 1

SUN3 Protein Structure

Sad1_UNC

0
100
200
300
357 a.a.

Protein Preferred Names

Protein Names

SUN domain-containing protein 3

Sad1 and UNC84 domain containing 1

Related Diseases

Diseases

Alias

Deafness, Autosomal Recessive 40

DFNB40	Autosomal Recessive Nonsyndromic Deafness 40
Autosomal Recessive Deafness 40

Deafness, Autosomal Recessive 55

DFNB55	Autosomal Recessive Nonsyndromic Deafness 55
Autosomal Recessive Deafness 55

Spermatogenic Failure 9

Male Infertility Due To Globozoospermia	SPGF9
Male Infertility Due To Round-Headed Spermatozoa	Globozoospermia, Complete
Globozoospermia, Total	Globozoospermia
Globozoospermia Syndrome	Round-Headed Sperm Syndrome
Globozoospermia Complete	Globozoospermia Total

Urocanase Deficiency

Encephalopathy Due To Urocanase Deficiency	Urocanate Hydratase Deficiency
Urocanic Aciduria	UROCD
High Urine Urocanic Acid Levels

Male Infertility Due To Acephalic Spermatozoa

Acephalic Spermatozoa Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS14031	SUN3 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	SUN3	VGNC	VGNC:81768
Mus musculus	SUN3	MGD	MGI:3041199
Rattus norvegicus	SUN3	RGD	RGD:1591975
Bos taurus	SUN3	VGNC	VGNC:35475
Felis catus	SUN3	VGNC	VGNC:65843
Canis familiaris	SUN3	VGNC	VGNC:46986