Il2ra - interleukin 2 receptor subunit alpha Gene

Also Known as IL2RAC

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25704

Summary

Enables interleukin-2 receptor activity. Involved in inflammatory response to antigenic stimulus; positive regulation of T cell differentiation; and positive regulation of T cell proliferation. Located in cell surface. Used to study Korean hemorrhagic fever; asthma; and diabetes mellitus. Human ortholog(s) of this gene implicated in immunodeficiency 41; lymphopenia; multiple sclerosis; type 1 diabetes mellitus; and type 1 diabetes mellitus 10. Orthologous to human IL2RA (interleukin 2 receptor subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]

Il2ra Products (1)

mRNA Protein Name
NM_013163.2 NP_037295.1 interleukin-2 receptor subunit alpha precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables interleukin-2 receptor activity IPI
IPI: Inferred from physical interaction
2592769 RGD
Biological Process GO Annotation Evidence References Source
involved in inflammatory response to antigenic stimulus IMP
IMP: Inferred from mutant phenotype
10389888 RGD
involved in positive regulation of T cell differentiation IMP
IMP: Inferred from mutant phenotype
9352365 RGD
involved in positive regulation of T cell proliferation IMP
IMP: Inferred from mutant phenotype
9352365 RGD
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
10210776 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

interleukin-2 receptor subunit alpha

  • IL-2 receptor alpha subunit

  • IL-2 receptor subunit alpha

  • IL-2-RA

  • IL-2R subunit alpha

  • IL2-RA

  • interleukin 2 receptor, alpha chain

Recombinant Il2ra Proteins

Cat. No. Product Name Accession Purity
HY-P74809 IL-2R alpha/CD25 Protein, Rat (sf9, His) P26897/NP_037295.1 (E22-Q235) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P990086 Vopikitug Inhibitor 98.32% Phase 1

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06748 IL2RA Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174611 Human IL2RA mRNA / Unkown
HY-RS18825 Il2ra Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25315 Il2ra Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P992161 REGN-10597 / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Il2ra NCBI NCBI:3559