Pfkl - phosphofructokinase, liver type Gene

Also Known as PFK-L; ATP-PFK

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25741

Summary

Enables several functions, including 6-phosphofructokinase activity; anion binding activity; and identical protein binding activity. Involved in fructose 1,6-bisphosphate metabolic process; fructose 6-phosphate metabolic process; and glycolytic process. Located in cytosol. Orthologous to human PFKL (phosphofructokinase, liver type). [provided by Alliance of Genome Resources, Apr 2022]

Pfkl Products (1)

mRNA Protein Name
NM_013190.4 NP_037322.1 ATP-dependent 6-phosphofructokinase, liver type

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables 6-phosphofructokinase activity IDA
IDA: Inferred from direct assay
156182 RGD
enables ATP binding IDA
IDA: Inferred from direct assay
156182 RGD
enables fructose-6-phosphate binding IDA
IDA: Inferred from direct assay
2931076 RGD
enables identical protein binding IPI
IPI: Inferred from physical interaction
2931076 RGD
enables monosaccharide binding IDA
IDA: Inferred from direct assay
156182 RGD
Biological Process GO Annotation Evidence References Source
involved in fructose 1,6-bisphosphate metabolic process IDA
IDA: Inferred from direct assay
2931076 RGD
involved in fructose 6-phosphate metabolic process IDA
IDA: Inferred from direct assay
156182 RGD
involved in glycolytic process IDA
IDA: Inferred from direct assay
2931076 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ATP-dependent 6-phosphofructokinase, liver type

  • 6-phosphofructokinase type B

  • 6-phosphofructokinase, liver type

  • PFK-B

  • phosphofructo-1-kinase isozyme B

  • phosphofructokinase 1

  • phosphofructokinase, liver, B-type

  • phosphohexokinase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-182002 Apoptosis inducer 61 / Unkown
HY-RS10365 PFKL Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18781 Pfkl Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25270 Pfkl Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pfkl NCBI NCBI:5211