C1orf43 - chromosome 1 open reading frame 43 Gene

Also Known as NICE3; NICE-3; S863-3; HSPC012; NS5ATP4

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 25912

About C1orf43

Cytogenetic location: 1q21.3 Genomic coordinates (GRCh38): 1:154,206,720-154,220,590 (from NCBI)

This gene has 11 transcripts (splice variants) and 264 orthologues. Ubiquitous expression in kidney (RPKM 53.9), fat (RPKM 47.2) and 25 other tissues.

Summary

Involved in phagocytosis. Located in Golgi apparatus and mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

C1orf43 Products (8)

mRNA Protein Name
NM_001098616.3 NP_001092086.1 protein C1orf43 isoform 3
NM_001297717.2 NP_001284646.1 protein C1orf43 isoform 4
NM_001297718.2 NP_001284647.1 protein C1orf43 isoform 5
NM_001297720.2 NP_001284649.1 protein C1orf43 isoform 6
NM_001297721.2 NP_001284650.1 protein C1orf43 isoform 7
NM_001297723.2 NP_001284652.1 protein C1orf43 isoform 8
NM_015449.4 NP_056264.1 protein C1orf43 isoform 1
NM_138740.4 NP_620077.1 protein C1orf43 isoform 2

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in phagocytosis IMP
IMP: Inferred from mutant phenotype
31540829 GOA
Cellular Component GO Annotation Evidence References Source
located in Golgi apparatus IDA
IDA: Inferred from direct assay
31540829 GOA
located in mitochondrion IDA
IDA: Inferred from direct assay
31540829 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

C1orf43 Protein Structure

NICE-3

NICE-3: NICE-3 protein (1 - 188)

  • 0
  • 100
  • 200
  • 253 a.a.
Protein Preferred Names Protein Names

protein C1orf43

  • HCV NS5A-transactivated protein 4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01715 C1orf43 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus C1orf43 VGNC VGNC:59177
Rattus norvegicus C1orf43 RGD RGD:1359625
Macaca mulatta C1orf43 VGNC VGNC:70442
Mus musculus C1orf43 MGD MGI:1914027
Felis catus C1orf43 VGNC VGNC:60803
Canis familiaris C1orf43 VGNC VGNC:55734
Others C1orf43 NCBI