Ehd2 - EH-domain containing 2 Gene

Also Known as C130052H20Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 259300

Summary

Enables identical protein binding activity and protein domain specific binding activity. Involved in several processes, including plasma membrane tubulation; positive regulation of endocytic recycling; and positive regulation of myoblast fusion. Acts upstream of or within cortical actin Cytoskeleton organization and endocytosis. Located in caveola; cytosol; and perinuclear region of cytoplasm. Is extrinsic component of membrane. Is expressed in aorta endothelium; blood vessel; brown fat; lymphatic vessel endothelium; and mesenteric artery. Orthologous to human EHD2 (EH domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]

Ehd2 Products (1)

mRNA Protein Name
NM_153068.3 NP_694708.2 EH domain-containing protein 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Références Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
17914359 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
15247266 MGI
enables protein domain specific binding IDA
IDA: Inferred from direct assay
14676205 MGI
Biological Process GO Annotation Evidence Références Source
acts upstream of or within cortical actin cytoskeleton organization IDA
IDA: Inferred from direct assay
15247266 MGI
acts upstream of or within endocytosis IDA
IDA: Inferred from direct assay
14676205 MGI
involved in plasma membrane tubulation IDA
IDA: Inferred from direct assay
24508342 MGI
involved in positive regulation of endocytic recycling IMP
IMP: Inferred from mutant phenotype
21177873 MGI
involved in positive regulation of myoblast fusion IMP
IMP: Inferred from mutant phenotype
21177873 MGI
involved in protein localization to plasma membrane IDA
IDA: Inferred from direct assay
21177873 MGI
Cellular Component GO Annotation Evidence Références Source
located in caveola IDA
IDA: Inferred from direct assay
24508342 MGI
located in cytosol IDA
IDA: Inferred from direct assay
24508342 MGI
located in membrane IDA
IDA: Inferred from direct assay
14676205 MGI
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
20489164 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
15247266 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

EH domain-containing protein 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-158415 ATPase-IN-4 98.25% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ehd2 NCBI NCBI:30846