2. Gene
  3. CYP4X1 - cytochrome P450 family 4 subfamily X member 1 Gene

CYP4X1 - cytochrome P450 family 4 subfamily X member 1 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as CYPIVX1

Gene ID: 260293 | Gene type: protein coding

About CYP4X1

Cytogenetic location: 1p33 Genomic coordinates (GRCh38): 1:46,961,364-47,055,432 (from NCBI)

This gene has 2 transcripts (splice variants), 397 orthologues and 12 paralogues. Broad expression in prostate (RPKM 4.4), lung (RPKM 4.1) and 23 other tissues.

Summary

This gene encodes a member of the Cytochrome P450 superfamily of enzymes and is located within a cluster of genes belonging to this superfamily on chromosome 1. The Cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of Cholesterol, Steroids and other lipids. The expression pattern of a similar rat protein suggests that this protein may be involved in neurovascular function in the brain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

CYP4X1 Products(3)

mRNA Protein Name
NM_001320289.2 NP_001307218.1 cytochrome P450 4X1 isoform 2
NM_001320290.2 NP_001307219.1 cytochrome P450 4X1 isoform 3
NM_178033.2 NP_828847.1 cytochrome P450 4X1 isoform 1

CYP4X1 Protein Structure

p450

p450: Cytochrome P450 (47 - 500)

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  • 509 a.a.
Protein Preferred Names Protein Names

cytochrome P450 4X1

cytochrome P450, family 4, subfamily X, polypeptide 1

Related Diseases

Diseases Alias
Bietti Crystalline Corneoretinal Dystrophy

BCD

Bietti Crystalline Dystrophy

Bietti Tapetoretinal Degeneration With Marginal Corneal Dystrophy

Bietti Crystalline Retinopathy

Bietti'S Crystalline Dystrophy

Crystalline Retinopathy

Dystrophy, Corneoretinal, Crystalline, Bietti
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03484 CYP4X1 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus CYP4X1 VGNC VGNC:103325
Macaca mulatta CYP4X1 VGNC VGNC:103614
Canis familiaris CYP4X1 VGNC VGNC:50372
Mus musculus CYP4X1 MGD MGI:1932403
Rattus norvegicus CYP4X1 RGD RGD:628719