Ccr9 - C-C motif chemokine receptor 9 Gene
Species: Rattus norvegicus
About Ccr9
This gene has 2 transcripts (splice variants), 265 orthologues, 24 paralogues and is associated with 5 phenotypes. Restricted expression toward (RPKM 438.1).
Summary
Predicted to enable C-C chemokine binding activity and C-C Chemokine Receptor activity. Predicted to be involved in several processes, including calcium-mediated signaling; cell chemotaxis; and positive regulation of cytosolic calcium ion concentration. Predicted to act upstream of or within CD8-positive, gamma-delta intraepithelial T cell differentiation and chemotaxis. Predicted to be located in cell surface. Predicted to be active in external side of plasma membrane. Orthologous to human CCR9 (C-C motif Chemokine Receptor 9). [provided by Alliance of Genome Resources, Apr 2022]
Ccr9 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_172329.1 | NP_758832.1 | C-C chemokine receptor type 9 |
Ccr9 Protein Structure
7tm_GPCRs: cl28897 (48 - 327)
7tm_GPCRs: cd14964 (50 - 74)
7tm_GPCRs: cd14964 (83 - 104)
7tm_GPCRs: cd14964 (119 - 141)
7tm_GPCRs: cd14964 (166 - 182)
7tm_GPCRs: cd14964 (211 - 234)
7tm_GPCRs: cd14964 (252 - 274)
7tm_GPCRs: cd14964 (295 - 320)
- 0
- 100
- 200
- 300
- 369 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
C-C chemokine receptor type 9 |
|
Related Agents
- Clinical Phase
- Pre-clinical Phase
Clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Phase
|
|---|---|---|---|---|
| HY-15724 | Vercirnon | Antagonist | 98.01% | Phase 3 |
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-15724A | Vercirnon sodium | Antagonist | 98.04% | Unkown |
| HY-181288 | CCR9 ligand-Linker Conjugate 1 | Ligand | / | Unkown |
| HY-181287 | PROTAC CCR9 Degrader 1 | Degrader | / | Unkown |
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