ZNF740 - zinc finger protein 740 Gene

Also Known as Zfp740

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 283337

About ZNF740

This gene has 4 transcripts (splice variants), 204 orthologues and 4 paralogues. Ubiquitous expression in thyroid (RPKM 8.1), ovary (RPKM 7.3) and 25 other tissues.

Summary

Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of chromatin. [provided by Alliance of Genome Resources, Apr 2022]

ZNF740 Products (1)

mRNA Protein Name
NM_001004304.4 NP_001004304.1 zinc finger protein 740

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
enables sequence-specific double-stranded DNA binding IDA
IDA: Inferred from direct assay
28473536 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZNF740 Protein Structure

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (115 - 138)

zf-H2C2_2

zf-H2C2_2: Zinc-finger double domain (143 - 167)

  • 0
  • 100
  • 193 a.a.
Protein Preferred Names Protein Names

zinc finger protein 740

  • oriLyt TD-element-binding protein 7

ZNF740 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
ZNF740 Q8NDX6 M1AP Homo sapiens Q8TC57
Y2H Prey Pooling
32296183
Intra
ZNF740 Q8NDX6 M1AP Homo sapiens Q8TC57
Y2H Array
32296183
Intra
ZNF740 Q8NDX6 M1AP Homo sapiens Q8TC57
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Ocular Tuberculosis
Phlyctenulosis

  • Phlyctenular Keratoconjunctivitis

  • Strumous Ophthalmia
Extrapulmonary Tuberculosis

  • EPTB

  • Tuberculosis, Extrapulmonary
Viral Gastritis
Pleural Tuberculosis

  • Pearly Disease

  • Tuberculosis Of Pleura

  • Tuberculous Pleurisy

  • Tuberculous Pleurisy In Primary Progressive Tuberculosis

  • Tuberculous Pleuritis

  • Pleurisy Tuberculous

  • Tuberculosis, Pleural

  • Serosal Tuberculosis Of Cattle
Multidrug-Resistant Tuberculosis

  • Tuberculosis, Multidrug-Resistant

  • Tuberculosis Multidrug-Resistant
Primary Bacterial Infectious Disease
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS16171 ZNF740 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus ZNF740 RGD RGD:1589052
Mus musculus ZNF740 MGD MGI:1915994
Canis familiaris ZNF740 VGNC VGNC:48809
Felis catus ZNF740 VGNC VGNC:67353
Macaca mulatta ZNF740 VGNC VGNC:79665
Others ZNF740 NCBI