Stk16 - serine/threonine kinase 16 Gene

Also Known as F52; PKL12

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 286927

Summary

Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and protein kinase activity. Involved in cellular response to transforming growth factor beta stimulus; positive regulation of transcription by RNA polymerase II; and protein autophosphorylation. Predicted to be located in several cellular components, including Golgi-associated vesicle; cytosol; and nucleoplasm. Predicted to be active in Golgi apparatus. Orthologous to human STK16 (serine/threonine kinase 16). [provided by Alliance of Genome Resources, Apr 2022]

Stk16 Products (1)

mRNA Protein Name
NM_173142.1 NP_775165.1 serine/threonine-protein kinase 16

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
10947953 RGD
enables protein kinase activity IDA
IDA: Inferred from direct assay
10947953 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to transforming growth factor beta stimulus IDA
IDA: Inferred from direct assay
10947953 RGD
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
10947953 RGD
involved in protein autophosphorylation IDA
IDA: Inferred from direct assay
10947953 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serine/threonine-protein kinase 16

  • MPSK

  • TGF-beta-stimulated factor 1

  • TSF-1

  • myristoylated and palmitoylated serine/threonine-protein kinase

  • protein kinase PKL12

  • tyrosine-protein kinase STK16

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-101270 STK16-IN-1 Inhibitor 99.81% Unkown
HY-19353 SR7826 Inhibitor 99.30% Unkown
HY-181293 PROTAC AAK1 degrader-1 Degrader 95.87% Unkown
HY-RS13923 STK16 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18549 Stk16 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25031 Stk16 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Stk16 NCBI NCBI:8576