STK16 - serine/threonine kinase 16 Gene

Homo sapiens

Also known as PSK; KRCT; MPSK; TSF1; hPSK; PKL12

Gene ID: 8576 | Gene type: protein coding

About STK16

Cytogenetic location: 2q35 Genomic coordinates (GRCh38): 2:219,245,479-219,250,337 (from NCBI)

This gene has 13 transcripts (splice variants), 205 orthologues and 2 paralogues. Ubiquitous expression in thyroid (RPKM 7.6), brain (RPKM 6.9) and 25 other tissues.

Summary

Predicted to enable protein serine/threonine kinase activity. Involved in protein autophosphorylation. Located in cytosol; nucleoplasm; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

STK16 Products(4)

mRNA	Protein	Name
NM_001008910.4	NP_001008910.1	serine/threonine-protein kinase 16 isoform 1
NM_001330213.2	NP_001317142.1	serine/threonine-protein kinase 16 isoform 1
NM_001330214.1	NP_001317143.1	serine/threonine-protein kinase 16 isoform 2
NM_001330215.2	NP_001317144.1	serine/threonine-protein kinase 16 isoform 3

STK16 Protein Structure

Pkinase

0
100
200
305 a.a.

Protein Preferred Names

Protein Names

serine/threonine-protein kinase 16

TGF-beta-stimulated factor 1

Recombinant STK16 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P76097	STK16 Protein, Human (His)	O75716 (M1-I305)	≥95%

Related Diseases

Diseases

Alias

Diffuse Mesangial Sclerosis

Familial Mesangial Sclerosis	Mesangial Sclerosis, Diffuse
Dms	Diffuse Isolated Mesangial Sclerosis
Isolated Diffuse Mesangial Sclerosis	Nephrotic Syndrome, Early Onset With Diffuse Mesangial Sclerosis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (3)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-19353	SR7826	Inhibitor	98.74%	Unkown
HY-101270	STK16-IN-1	Inhibitor	99.95%	Unkown
HY-RS13923	STK16 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	STK16	VGNC	VGNC:65776
Mus musculus	STK16	MGD	MGI:1313271
Rattus norvegicus	STK16	RGD	RGD:629474
Canis familiaris	STK16	VGNC	VGNC:46906
Bos taurus	STK16	VGNC	VGNC:35387
Macaca mulatta	STK16	VGNC	VGNC:77912
Others	STK16	NCBI

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