NHP2 - Nhp2 NHP2 ribonucleoprotein Gene

Also Known as Nola2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 287273

Summary

Enables U3 snoRNA binding activity and mRNA 3'-UTR binding activity. Involved in snoRNA guided rRNA pseudouridine synthesis. Part of box H/ACA snoRNP complex. Human ortholog(s) of this gene implicated in autosomal recessive dyskeratosis congenita 2. Orthologous to human NHP2 (NHP2 ribonucleoprotein). [provided by Alliance of Genome Resources, Apr 2022]

NHP2 Products (1)

mRNA Protein Name
NM_001414279.1 NP_001401208.1 H/ACA ribonucleoprotein complex subunit 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables U3 snoRNA binding IDA
IDA: Inferred from direct assay
15044956 RGD
enables mRNA 3'-UTR binding IDA
IDA: Inferred from direct assay
15044956 RGD
Biological Process GO Annotation Evidence References Source
involved in snoRNA guided rRNA pseudouridine synthesis IDA
IDA: Inferred from direct assay
12446766 RGD
Cellular Component GO Annotation Evidence References Source
part of box H/ACA snoRNP complex IDA
IDA: Inferred from direct assay
12446766 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

H/ACA ribonucleoprotein complex subunit 2

  • H/ACA ribonucleoprotein complex subunit 2-like

  • nucleolar protein family A, member 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09289 NHP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19623 Nhp2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26118 Nhp2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens NHP2 NCBI NCBI:55651