Serpinf2 - serpin family F member 2 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 287527

Summary

Enables serine-type endopeptidase inhibitor activity. Involved in negative regulation of fibrinolysis and response to organic substance. Located in extracellular space. Used to study acute necrotizing pancreatitis. Biomarker of familial hyperlipidemia. Human ortholog(s) of this gene implicated in COVID-19 and alpha-2-plasmin inhibitor deficiency. Orthologous to human SERPINF2 (Serpin family F member 2). [provided by Alliance of Genome Resources, Apr 2022]

Serpinf2 Products (1)

mRNA Protein Name
NM_001011892.1 NP_001011892.1 alpha-2-antiplasmin precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables serine-type endopeptidase inhibitor activity IDA
IDA: Inferred from direct assay
6438828 RGD
Biological Process GO Annotation Evidence References Source
involved in negative regulation of fibrinolysis IMP
IMP: Inferred from mutant phenotype
6506034 RGD
Cellular Component GO Annotation Evidence References Source
located in extracellular space IDA
IDA: Inferred from direct assay
10423332 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

alpha-2-antiplasmin

  • serine (or cysteine) peptidase inhibitor, clade F, member 2

  • serine (or cysteine) proteinase inhibitor, clade F, member 2

  • serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2

Recombinant Serpinf2 Proteins

Cat. No. Product Name Accession Purity
HY-P76721 Alpha-2-Antiplasmin/Serpin F2 Protein, Rat (HEK293, His) Q68FT8 (M28-K491) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12726 SERPINF2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19292 Serpinf2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25782 Serpinf2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Serpinf2 NCBI NCBI:5345
Macaca fascicularis Serpinf2 NCBI NCBI:102116557
Mus musculus Serpinf2 NCBI NCBI:18816