Aimp2 - aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 Gene

Also Known as Jtv1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 288480

Summary

Predicted to enable molecular adaptor activity. Acts upstream of or within positive regulation of neuron death. Part of Aminoacyl-tRNA Synthetase multienzyme complex. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy. Orthologous to human AIMP2 (aminoacyl tRNA synthetase complex interacting multifunctional protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Aimp2 Products (1)

mRNA Protein Name
NM_001037348.1 NP_001032425.1 aminoacyl tRNA synthase complex-interacting multifunctional protein 2

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within positive regulation of neuron apoptotic process IDA
IDA: Inferred from direct assay
20823226 RGD
Cellular Component GO Annotation Evidence References Source
part of aminoacyl-tRNA synthetase multienzyme complex IDA
IDA: Inferred from direct assay
19524539 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

aminoacyl tRNA synthase complex-interacting multifunctional protein 2

  • JTV1

  • multisynthase complex auxiliary component p38

  • multisynthetase complex auxiliary component p38

  • protein JTV-1

  • rCG42778-like

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-136431 BC-DXI-843 Inhibitor 99.76% Unkown
HY-150719 AIMP2-DX2-IN-1 ≥98.0% Unkown
HY-182399 BC-DXI-495 Inhibitor / Unkown
HY-RS00498 AIMP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20364 Aimp2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26873 Aimp2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Aimp2 NCBI NCBI:7965