Arpc3 - actin related protein 2/3 complex, subunit 3 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 288669

About Arpc3

Primary_assembly 12: 34,172,780-34,186,651 reverse strand.mRatBN7.2:CM026985.1

This gene has 3 transcripts (splice variants), 286 orthologues and is associated with 2 phenotypes. Biased expression in Thymus (RPKM 834.3), Spleen (RPKM 74.2) and 9 other tissues.

Summary

Predicted to be a structural constituent of Cytoskeleton. Predicted to contribute to actin filament binding activity. Involved in cellular response to nerve growth factor stimulus. Located in growth cone leading edge. Part of filamentous actin. Used to study Parkinson's disease. Orthologous to human ARPC3 (actin related protein 2/3 complex subunit 3). [provided by Alliance of Genome Resources, Apr 2022]

Arpc3 Products (1)

mRNA Protein Name
NM_001105933.1 NP_001099403.1 actin-related protein 2月3日 complex subunit 3

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in cellular response to nerve growth factor stimulus IEP
IEP: Inferred from expression pattern
10797548 RGD
Cellular Component GO Annotation Evidence References Source
located in cell leading edge IDA
IDA: Inferred from direct assay
10209028 RGD
part of filamentous actin IDA
IDA: Inferred from direct assay
10797548 RGD
located in growth cone leading edge IDA
IDA: Inferred from direct assay
10797548 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Arpc3 Protein Structure

P21-Arc

P21-Arc: pfam04062 (0 - 172)

  • 0
  • 100
  • 178 a.a.
Protein Preferred Names Protein Names

actin-related protein 2/3 complex subunit 3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01018 ARPC3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01019 Arpc3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01020 Arpc3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Arpc3 NCBI NCBI:10094