REM1 - RRAD and GEM like GTPase 1 Gene

Also Known as GES; GD:REM

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 28954

About REM1

Cytogenetic location: 20q11.21 Genomic coordinates (GRCh38): 20:31,475,288-31,484,895 (from NCBI)

This gene has 1 transcript (splice variant), 169 orthologues and 35 paralogues. Broad expression in fat (RPKM 3.0), endometrium (RPKM 2.6) and 21 other tissues.

Summary

The protein encoded by this gene is a GTPase and member of the RAS-like GTP-binding protein family. The encoded protein is expressed in endothelial cells, where it promotes reorganization of the actin Cytoskeleton and morphological changes in the cells. [provided by RefSeq, Jul 2008]

REM1 Products (1)

mRNA Protein Name
NM_014012.6 NP_054731.2 GTP-binding protein REM 1

REM1 Protein Structure

Ras

Ras: Ras family (82 - 243)

  • 0
  • 100
  • 200
  • 298 a.a.
Protein Preferred Names Protein Names

GTP-binding protein REM 1

  • GTPase-regulating endothelial cell sprouting

Related Diseases

Diseases Alias
Mobitz Type Ii Atrioventricular Block

  • Mobitz Ii Atrioventricular Block

  • Mobitz Ii Atrioventricular Block
Immunodeficiency 18

  • IMD18

  • Cd3-Epsilon Deficiency

  • Immunodeficiency 18, Scid Variant

  • Cd3epsilon Deficiency

  • Immunodeficiency 18, Severe Combined Immunodeficiency Variant

  • Immunodeficiency, Type 18
Parkinson Disease, Late-Onset

  • Parkinson Disease

  • Parkinson'S Disease

  • PD

  • PARK

  • Parkinson Disease, Susceptibility To

  • Late Onset Parkinson'S Disease

  • Late Onset Parkinson Disease

  • Paralysis Agitans

  • Primary Parkinsonism

  • Idiopathic Parkinson Disease

  • Parkinson'S

  • Parkinson Disease, Late-Onset, Susceptibility To

  • Parkinson Disease, Age Of Onset, Modifier

  • Lewy Body Parkinson Disease

  • Idiopathic Parkinson'S Disease

  • Pd - [Parkinson Disease]

  • Parkinson Disease Nos

  • Parkinson, Nos

  • Primary Parkinson Disease
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11837 REM1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19637 Rem1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25867 Rcn3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26131 Rem1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus REM1 VGNC VGNC:33863
Macaca mulatta REM1 VGNC VGNC:108026
Mus musculus REM1 MGD MGI:1097696
Canis familiaris REM1 VGNC VGNC:45472
Rattus norvegicus REM1 RGD RGD:1306560
Felis catus REM1 VGNC VGNC:64569
Others REM1 NCBI