Ctf1 - cardiotrophin 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29201

Summary

Enables cytokine activity and Leukemia Inhibitory Factor receptor binding activity. Involved in Leukemia Inhibitory Factor signaling pathway and nervous system development. Predicted to be located in extracellular space. Predicted to be active in extracellular region. Biomarker of hypertension. Human ortholog(s) of this gene implicated in dilated cardiomyopathy. Orthologous to human CTF1 (cardiotrophin 1). [provided by Alliance of Genome Resources, Apr 2022]

Ctf1 Products (1)

mRNA Protein Name
NM_017129.1 NP_058825.1 cardiotrophin-1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables cytokine activity IMP
IMP: Inferred from mutant phenotype
15623435 RGD
enables leukemia inhibitory factor receptor binding IMP
IMP: Inferred from mutant phenotype
15623435 RGD
Biological Process GO Annotation Evidence References Source
involved in leukemia inhibitory factor signaling pathway IMP
IMP: Inferred from mutant phenotype
15623435 RGD
involved in nervous system development IDA
IDA: Inferred from direct assay
11932952 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cardiotrophin-1

  • CT-1

Recombinant Ctf1 Proteins

Cat. No. Product Name Accession Purity
HY-P71924 Cardiotrophin-1/CTF1 Protein, Rat Q63086 (M1-A203) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-123761 L505-yne Inhibitor / Unkown
HY-RS03295 CTF1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17741 Ctf1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24207 Ctf1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ctf1 NCBI NCBI:1489