Mgll - monoglyceride lipase Gene

Also Known as MAGL

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 29254

Summary

Enables acylglycerol Lipase activity. Involved in monoacylglycerol catabolic process and positive regulation of vasoconstriction. Located in synapse. Orthologous to human MGLL (monoglyceride Lipase). [provided by Alliance of Genome Resources, Apr 2022]

Mgll Products (2)

mRNA Protein Name
NM_001398597.1 NP_001385526.1 monoglyceride lipase isoform 1
NM_138502.3 NP_612511.1 monoglyceride lipase isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables hydrolase activity IDA
IDA: Inferred from direct assay
12136125 RGD
enables monoacylglycerol lipase activity IDA
IDA: Inferred from direct assay
17649977 RGD
Biological Process GO Annotation Evidence References Source
involved in monoacylglycerol catabolic process IDA
IDA: Inferred from direct assay
17649977 RGD
involved in positive regulation of vasoconstriction IMP
IMP: Inferred from mutant phenotype
17245358 RGD
Cellular Component GO Annotation Evidence References Source
is active in presynapse IDA
IDA: Inferred from direct assay
15233753 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

monoglyceride lipase

  • MGL

  • monoacylglycerol lipase

Recombinant Mgll Proteins

Cat. No. Product Name Accession Purity
HY-P71755 Monoglyceride lipase Protein, Rat (P.pastoris, His) Q8R431 (M1-P303) ≥ 90%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-18540 KT109 Inhibitor 99.86% Unkown
HY-124576 ABD-1970 Inhibitor / Unkown
HY-RS08409 MGLL Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16868 Mgll Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23309 Mgll Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24917 Clec10a Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mgll NCBI NCBI:11343