AURKC - aurora kinase C Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 292554

About AURKC

Primary_assembly 1: 66,843,653-66,864,386 reverse strand.mRatBN7.2:CM026974.1

This gene has 3 transcripts (splice variants), 99 orthologues, 2 paralogues and is associated with 4 phenotypes. Biased expression in Testes (RPKM 91.3), Brain (RPKM 4.2) and 9 other tissues.

Summary

Predicted to enable histone serine kinase activity. Predicted to be involved in mitotic spindle organization; protein phosphorylation; and regulation of cytokinesis. Predicted to act upstream of or within protein autophosphorylation. Predicted to be located in chromosome; meiotic spindle midzone; and midbody. Predicted to be part of chromosome passenger complex. Predicted to be active in spindle microtubule; spindle midzone; and spindle pole centrosome. Human ortholog(s) of this gene implicated in spermatogenic failure 5. Orthologous to human AURKC (Aurora Kinase C). [provided by Alliance of Genome Resources, Apr 2022]

AURKC Products (1)

mRNA Protein Name
NM_001308536.1 NP_001295465.1 aurora kinase C

AURKC Protein Structure

PKc_like

PKc_like: cl21453 (55 - 324)

  • 0
  • 100
  • 200
  • 300
  • 329 a.a.
Protein Preferred Names Protein Names

aurora kinase C

  • serine/threonine-protein kinase 13

  • zinc finger protein 264-like

  • zinc finger protein 805-like

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-175525 MS44 Degrader 99.89% Unkown
HY-120279A CFI-400437 Inhibitor / Unkown
HY-123610 BRD-7880 Inhibitor / Unkown
HY-160691 GW814408X Inhibitor / Unkown
HY-RS01273 AURKC Human Pre-designed siRNA Set A / Unkown
HY-RS01274 Aurkc Mouse Pre-designed siRNA Set A / Unkown
HY-RS01275 AURKC Rat Pre-designed siRNA Set A / Unkown
HY-119948 AKCI Modulator / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens AURKC NCBI NCBI:6795