BRD-7880
BRD-7880 is a potent and highly specific inhibitor of Aurora Kinase B (AURKB) and Aurora Kinase C (AURKC), with IC50 values of 7 nM and 12 nM, respectively.
For research use only. We do not sell to patients.
- CAS No.: 1456542-69-0
- Formula: C32H38N4O7
- Molecular Weight:590.67
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Protocols
- Purity & Documentation
- References
-
Help & FAQs
All Aurora Kinase Isoforms
More
Biological Activity
Description
IC50 & Target
|
Aurora B 7 nM (IC50) |
Aurora C 12 nM (IC50) |
Aurora A 2153 nM (IC50) |
Chemical Information
-
CAS No. 1456542-69-0
-
Molecular Weight 590.67
-
Formula C32H38N4O7
-
SMILES
O=C1C2=CC(NC(NC3=CC=C(C=C3)OC)=O)=CC=C2O[C@H]([C@H](CN1[C@@H](C)CO)C)CN(C)CC4=CC=C(OCO5)C5=C4
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
-
Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BRD-7880 Related Classifications
HY-123610 Related Classifications
Powered by Bioz